node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Rxyl_1244 | aroA | Rxyl_1244 | Rxyl_1441 | PFAM: prephenate dehydratase Chorismate mutase amino acid-binding ACT; KEGG: aae:aq_951 chorismate mutase/prephenate dehydratase. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.940 |
Rxyl_1244 | aroB | Rxyl_1244 | Rxyl_1459 | PFAM: prephenate dehydratase Chorismate mutase amino acid-binding ACT; KEGG: aae:aq_951 chorismate mutase/prephenate dehydratase. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.818 |
Rxyl_1244 | aroC | Rxyl_1244 | Rxyl_1461 | PFAM: prephenate dehydratase Chorismate mutase amino acid-binding ACT; KEGG: aae:aq_951 chorismate mutase/prephenate dehydratase. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.991 |
Rxyl_1244 | aroE | Rxyl_1244 | Rxyl_1362 | PFAM: prephenate dehydratase Chorismate mutase amino acid-binding ACT; KEGG: aae:aq_951 chorismate mutase/prephenate dehydratase. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.827 |
Rxyl_1244 | aroK | Rxyl_1244 | Rxyl_1460 | PFAM: prephenate dehydratase Chorismate mutase amino acid-binding ACT; KEGG: aae:aq_951 chorismate mutase/prephenate dehydratase. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.867 |
Rxyl_1244 | aroQ | Rxyl_1244 | Rxyl_1588 | PFAM: prephenate dehydratase Chorismate mutase amino acid-binding ACT; KEGG: aae:aq_951 chorismate mutase/prephenate dehydratase. | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.739 |
Rxyl_1360 | alaS | Rxyl_1360 | Rxyl_1359 | Holliday junction resolvase YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | 0.946 |
Rxyl_1360 | aroE | Rxyl_1360 | Rxyl_1362 | Holliday junction resolvase YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.830 |
Rxyl_1360 | mltG | Rxyl_1360 | Rxyl_1361 | Holliday junction resolvase YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. | Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. | 0.831 |
Rxyl_1360 | nifU/mnmA | Rxyl_1360 | Rxyl_1354 | Holliday junction resolvase YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins; In the N-terminal section; belongs to the NifU family. | 0.773 |
alaS | Rxyl_1360 | Rxyl_1359 | Rxyl_1360 | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | Holliday junction resolvase YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. | 0.946 |
alaS | aroE | Rxyl_1359 | Rxyl_1362 | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.818 |
alaS | mltG | Rxyl_1359 | Rxyl_1361 | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. | 0.861 |
alaS | nifU/mnmA | Rxyl_1359 | Rxyl_1354 | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins; In the N-terminal section; belongs to the NifU family. | 0.814 |
aroA | Rxyl_1244 | Rxyl_1441 | Rxyl_1244 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | PFAM: prephenate dehydratase Chorismate mutase amino acid-binding ACT; KEGG: aae:aq_951 chorismate mutase/prephenate dehydratase. | 0.940 |
aroA | aroB | Rxyl_1441 | Rxyl_1459 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.993 |
aroA | aroC | Rxyl_1441 | Rxyl_1461 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.994 |
aroA | aroE | Rxyl_1441 | Rxyl_1362 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.984 |
aroA | aroK | Rxyl_1441 | Rxyl_1460 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.989 |
aroB | Rxyl_1244 | Rxyl_1459 | Rxyl_1244 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | PFAM: prephenate dehydratase Chorismate mutase amino acid-binding ACT; KEGG: aae:aq_951 chorismate mutase/prephenate dehydratase. | 0.818 |