node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Rxyl_0975 | Rxyl_2791 | Rxyl_0975 | Rxyl_2791 | FO synthase subunit 1 / FO synthase subunit 2; KEGG: eba:p2A350 hypothetical protein; TIGRFAM: conserved hypothetical protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB. | KEGG: mta:Moth_0867 phosphomethylpyrimidine kinase; TIGRFAM: Phosphomethylpyrimidine kinase type-2; PFAM: Phosphomethylpyrimidine kinase type-1. | 0.460 |
Rxyl_0975 | thiE | Rxyl_0975 | Rxyl_2395 | FO synthase subunit 1 / FO synthase subunit 2; KEGG: eba:p2A350 hypothetical protein; TIGRFAM: conserved hypothetical protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.754 |
Rxyl_0975 | thiE-2 | Rxyl_0975 | Rxyl_2788 | FO synthase subunit 1 / FO synthase subunit 2; KEGG: eba:p2A350 hypothetical protein; TIGRFAM: conserved hypothetical protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.754 |
Rxyl_0975 | thiG | Rxyl_0975 | Rxyl_2396 | FO synthase subunit 1 / FO synthase subunit 2; KEGG: eba:p2A350 hypothetical protein; TIGRFAM: conserved hypothetical protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB. | Thiamine biosynthesis protein ThiS; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.986 |
Rxyl_0975 | thiM | Rxyl_0975 | Rxyl_2790 | FO synthase subunit 1 / FO synthase subunit 2; KEGG: eba:p2A350 hypothetical protein; TIGRFAM: conserved hypothetical protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.553 |
Rxyl_2784 | Rxyl_2789 | Rxyl_2784 | Rxyl_2789 | Transcriptional activator, TenA family; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | ThiW; TIGRFAM: ThiW; KEGG: pai:PAE2529 hypothetical protein. | 0.410 |
Rxyl_2784 | Rxyl_2791 | Rxyl_2784 | Rxyl_2791 | Transcriptional activator, TenA family; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | KEGG: mta:Moth_0867 phosphomethylpyrimidine kinase; TIGRFAM: Phosphomethylpyrimidine kinase type-2; PFAM: Phosphomethylpyrimidine kinase type-1. | 0.999 |
Rxyl_2784 | Rxyl_2792 | Rxyl_2784 | Rxyl_2792 | Transcriptional activator, TenA family; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | Transcriptional activator, TenA family; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4- amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2- methylpyrimidine (HMP); Belongs to the TenA family. | 0.942 |
Rxyl_2784 | thiE | Rxyl_2784 | Rxyl_2395 | Transcriptional activator, TenA family; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.824 |
Rxyl_2784 | thiE-2 | Rxyl_2784 | Rxyl_2788 | Transcriptional activator, TenA family; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.824 |
Rxyl_2784 | thiG | Rxyl_2784 | Rxyl_2396 | Transcriptional activator, TenA family; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | Thiamine biosynthesis protein ThiS; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.965 |
Rxyl_2784 | thiM | Rxyl_2784 | Rxyl_2790 | Transcriptional activator, TenA family; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.983 |
Rxyl_2787 | Rxyl_2789 | Rxyl_2787 | Rxyl_2789 | PFAM: NUDIX hydrolase; KEGG: dra:DR0329 MutT/NUDIX family protein; Belongs to the Nudix hydrolase family. | ThiW; TIGRFAM: ThiW; KEGG: pai:PAE2529 hypothetical protein. | 0.746 |
Rxyl_2787 | Rxyl_2791 | Rxyl_2787 | Rxyl_2791 | PFAM: NUDIX hydrolase; KEGG: dra:DR0329 MutT/NUDIX family protein; Belongs to the Nudix hydrolase family. | KEGG: mta:Moth_0867 phosphomethylpyrimidine kinase; TIGRFAM: Phosphomethylpyrimidine kinase type-2; PFAM: Phosphomethylpyrimidine kinase type-1. | 0.709 |
Rxyl_2787 | Rxyl_2792 | Rxyl_2787 | Rxyl_2792 | PFAM: NUDIX hydrolase; KEGG: dra:DR0329 MutT/NUDIX family protein; Belongs to the Nudix hydrolase family. | Transcriptional activator, TenA family; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4- amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2- methylpyrimidine (HMP); Belongs to the TenA family. | 0.689 |
Rxyl_2787 | thiE-2 | Rxyl_2787 | Rxyl_2788 | PFAM: NUDIX hydrolase; KEGG: dra:DR0329 MutT/NUDIX family protein; Belongs to the Nudix hydrolase family. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.790 |
Rxyl_2787 | thiL | Rxyl_2787 | Rxyl_2786 | PFAM: NUDIX hydrolase; KEGG: dra:DR0329 MutT/NUDIX family protein; Belongs to the Nudix hydrolase family. | Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. | 0.782 |
Rxyl_2787 | thiM | Rxyl_2787 | Rxyl_2790 | PFAM: NUDIX hydrolase; KEGG: dra:DR0329 MutT/NUDIX family protein; Belongs to the Nudix hydrolase family. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.702 |
Rxyl_2789 | Rxyl_2784 | Rxyl_2789 | Rxyl_2784 | ThiW; TIGRFAM: ThiW; KEGG: pai:PAE2529 hypothetical protein. | Transcriptional activator, TenA family; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | 0.410 |
Rxyl_2789 | Rxyl_2787 | Rxyl_2789 | Rxyl_2787 | ThiW; TIGRFAM: ThiW; KEGG: pai:PAE2529 hypothetical protein. | PFAM: NUDIX hydrolase; KEGG: dra:DR0329 MutT/NUDIX family protein; Belongs to the Nudix hydrolase family. | 0.746 |