STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rxyl_2903TIGRFAM: 4-aminobutyrate aminotransferase; PFAM: aminotransferase class-III; KEGG: tfu:Tfu_0690 bacterial 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (438 aa)    
Predicted Functional Partners:
Rxyl_1716
TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: bha:BH2312 methylmalonate-semialdehyde dehydrogenase.
 
 0.922
Rxyl_1749
PFAM: aldehyde dehydrogenase; KEGG: mac:MA4079 aldehyde dehydrogenase (NAD(P)+).
 
 0.922
Rxyl_2380
PFAM: aldehyde dehydrogenase; KEGG: reu:Reut_A2614 aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family.
 
 0.922
Rxyl_2456
PFAM: aldehyde dehydrogenase; KEGG: sco:SCO4780 putative aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.922
Rxyl_2905
PFAM: aldehyde dehydrogenase; KEGG: btk:BT9727_0295 succinate-semialdehyde dehydrogenase (NAD(P)+).
 
 0.922
Rxyl_3175
Succinate-semialdehyde dehydrogenase (NAD(P)+); PFAM: aldehyde dehydrogenase; KEGG: ade:Adeh_3025 aldehyde dehydrogenase.
 
 0.922
Rxyl_2453
PFAM: Enoyl-CoA hydratase/isomerase 3-hydroxyacyl-CoA dehydrogenase-like 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; KEGG: sru:SRU_1459 fatty oxidation complex, alpha subunit; Belongs to the enoyl-CoA hydratase/isomerase family.
   
 0.915
panC
Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
     
 0.903
Rxyl_0425
PFAM: 6-phosphogluconate dehydrogenase, NAD-binding; KEGG: sma:SAV1542 putative dehydrogenase.
     
  0.900
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 
 0.812
Your Current Organism:
Rubrobacter xylanophilus
NCBI taxonomy Id: 266117
Other names: R. xylanophilus DSM 9941, Rubrobacter xylanophilus DSM 9941, Rubrobacter xylanophilus str. DSM 9941, Rubrobacter xylanophilus strain DSM 9941
Server load: medium (74%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.