node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Rmet_1170 | hemA | Rmet_1170 | Rmet_3200 | Cytochrome c biogenesis protein, transmembrane region. | Glutamyl tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.465 |
Rmet_1170 | hemE | Rmet_1170 | Rmet_3491 | Cytochrome c biogenesis protein, transmembrane region. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.542 |
Rmet_1170 | hemL | Rmet_1170 | Rmet_0667 | Cytochrome c biogenesis protein, transmembrane region. | Glutamate-1-semialdehyde aminotransferase (aminomutase). | 0.616 |
Rmet_3492 | hemE | Rmet_3492 | Rmet_3491 | Esterase/lipase. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.517 |
Rmet_3492 | hemL | Rmet_3492 | Rmet_0667 | Esterase/lipase. | Glutamate-1-semialdehyde aminotransferase (aminomutase). | 0.687 |
cysG | hemA | Rmet_2811 | Rmet_3200 | Siroheme synthase (includes: uroporphyrin-III C-methyltransferase; precorrin-2 oxidase; ferrochelatase); Belongs to the precorrin methyltransferase family. | Glutamyl tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.734 |
cysG | hemB | Rmet_2811 | Rmet_3286 | Siroheme synthase (includes: uroporphyrin-III C-methyltransferase; precorrin-2 oxidase; ferrochelatase); Belongs to the precorrin methyltransferase family. | Porphobilinogen synthase; Belongs to the ALAD family. | 0.847 |
cysG | hemC | Rmet_2811 | Rmet_2749 | Siroheme synthase (includes: uroporphyrin-III C-methyltransferase; precorrin-2 oxidase; ferrochelatase); Belongs to the precorrin methyltransferase family. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.983 |
cysG | hemDX | Rmet_2811 | Rmet_2748 | Siroheme synthase (includes: uroporphyrin-III C-methyltransferase; precorrin-2 oxidase; ferrochelatase); Belongs to the precorrin methyltransferase family. | Putative bifunctional protein (uroporphyrinogen-III synthase transmembrane protein and Uroporphyrin-III C-methyltransferase). | 0.939 |
cysG | hemE | Rmet_2811 | Rmet_3491 | Siroheme synthase (includes: uroporphyrin-III C-methyltransferase; precorrin-2 oxidase; ferrochelatase); Belongs to the precorrin methyltransferase family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.919 |
cysG | hemL | Rmet_2811 | Rmet_0667 | Siroheme synthase (includes: uroporphyrin-III C-methyltransferase; precorrin-2 oxidase; ferrochelatase); Belongs to the precorrin methyltransferase family. | Glutamate-1-semialdehyde aminotransferase (aminomutase). | 0.705 |
cysG | nirE | Rmet_2811 | Rmet_3168 | Siroheme synthase (includes: uroporphyrin-III C-methyltransferase; precorrin-2 oxidase; ferrochelatase); Belongs to the precorrin methyltransferase family. | Uroporphyrin-III C-methyltransferase (Urogen III methylase) (SUMT) (Uroporphyrinogen III methylase) (UROM). | 0.920 |
hemA | Rmet_1170 | Rmet_3200 | Rmet_1170 | Glutamyl tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Cytochrome c biogenesis protein, transmembrane region. | 0.465 |
hemA | cysG | Rmet_3200 | Rmet_2811 | Glutamyl tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Siroheme synthase (includes: uroporphyrin-III C-methyltransferase; precorrin-2 oxidase; ferrochelatase); Belongs to the precorrin methyltransferase family. | 0.734 |
hemA | hemB | Rmet_3200 | Rmet_3286 | Glutamyl tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Porphobilinogen synthase; Belongs to the ALAD family. | 0.872 |
hemA | hemC | Rmet_3200 | Rmet_2749 | Glutamyl tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.975 |
hemA | hemDX | Rmet_3200 | Rmet_2748 | Glutamyl tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Putative bifunctional protein (uroporphyrinogen-III synthase transmembrane protein and Uroporphyrin-III C-methyltransferase). | 0.631 |
hemA | hemE | Rmet_3200 | Rmet_3491 | Glutamyl tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.698 |
hemA | hemL | Rmet_3200 | Rmet_0667 | Glutamyl tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Glutamate-1-semialdehyde aminotransferase (aminomutase). | 0.988 |
hemA | nirE | Rmet_3200 | Rmet_3168 | Glutamyl tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Uroporphyrin-III C-methyltransferase (Urogen III methylase) (SUMT) (Uroporphyrinogen III methylase) (UROM). | 0.756 |