node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
amtB | glnA | Rmet_0241 | Rmet_2062 | Ammonium transporter. | Glutamine synthetase. | 0.553 |
amtB | glnB | Rmet_0241 | Rmet_0681 | Ammonium transporter. | Regulatory protein P-II for glutamine synthetase. | 0.997 |
amtB | glnD | Rmet_0241 | Rmet_1433 | Ammonium transporter. | Uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism. | 0.505 |
amtB | glnE | Rmet_0241 | Rmet_0994 | Ammonium transporter. | Glutamine synthetase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transducti [...] | 0.434 |
amtB | glnK | Rmet_0241 | Rmet_0240 | Ammonium transporter. | Nitrogen regulatory protein PII-2; Belongs to the P(II) protein family. | 0.999 |
amtB | glnL | Rmet_0241 | Rmet_2060 | Ammonium transporter. | NtrB, signal transduction histidine kinase; nitrogen specific. | 0.731 |
amtB | gltB | Rmet_0241 | Rmet_3263 | Ammonium transporter. | Glutamate synthase, large subunit. | 0.804 |
glnA | amtB | Rmet_2062 | Rmet_0241 | Glutamine synthetase. | Ammonium transporter. | 0.553 |
glnA | glnB | Rmet_2062 | Rmet_0681 | Glutamine synthetase. | Regulatory protein P-II for glutamine synthetase. | 0.504 |
glnA | glnD | Rmet_2062 | Rmet_1433 | Glutamine synthetase. | Uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism. | 0.600 |
glnA | glnE | Rmet_2062 | Rmet_0994 | Glutamine synthetase. | Glutamine synthetase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transducti [...] | 0.783 |
glnA | glnK | Rmet_2062 | Rmet_0240 | Glutamine synthetase. | Nitrogen regulatory protein PII-2; Belongs to the P(II) protein family. | 0.514 |
glnA | glnL | Rmet_2062 | Rmet_2060 | Glutamine synthetase. | NtrB, signal transduction histidine kinase; nitrogen specific. | 0.736 |
glnA | gltB | Rmet_2062 | Rmet_3263 | Glutamine synthetase. | Glutamate synthase, large subunit. | 0.827 |
glnB | amtB | Rmet_0681 | Rmet_0241 | Regulatory protein P-II for glutamine synthetase. | Ammonium transporter. | 0.997 |
glnB | glnA | Rmet_0681 | Rmet_2062 | Regulatory protein P-II for glutamine synthetase. | Glutamine synthetase. | 0.504 |
glnB | glnD | Rmet_0681 | Rmet_1433 | Regulatory protein P-II for glutamine synthetase. | Uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism. | 0.975 |
glnB | glnL | Rmet_0681 | Rmet_2060 | Regulatory protein P-II for glutamine synthetase. | NtrB, signal transduction histidine kinase; nitrogen specific. | 0.965 |
glnB | gltB | Rmet_0681 | Rmet_3263 | Regulatory protein P-II for glutamine synthetase. | Glutamate synthase, large subunit. | 0.600 |
glnD | amtB | Rmet_1433 | Rmet_0241 | Uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism. | Ammonium transporter. | 0.505 |