STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
icmFMethylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly (By similarity). Does not exhibit methylmalonyl- CoA mutase (MCM) activity. (1272 aa)    
Predicted Functional Partners:
Bxe_B0292
Acetyl-CoA hydrolase.
  
 
 0.976
Bxe_B0397
Acetyl-CoA hydrolase.
  
 
 0.976
Bxe_B1860
Acetyl-CoA hydrolase.
  
 
 0.976
Bxe_B1384
Urea amidolyase-related protein.
  
 
 0.954
Bxe_A0285
Oxidoreductase.
  
 
 0.952
Bxe_A4290
Putative indolepyruvate ferredoxin oxidoreductase alpha and beta subunits.
  
 
 0.952
Bxe_B0361
Putative oxidoreductase.
  
 
 0.952
Bxe_C0614
Putative oxidoreductase.
  
 
 0.952
sucC
succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 
 
 0.927
Bxe_B0315
Putative acetoin dehydrogenase.
  
 
 0.925
Your Current Organism:
Paraburkholderia xenovorans
NCBI taxonomy Id: 266265
Other names: Burkholderia cepacia LB400, Burkholderia fungorum LB400, Burkholderia sp. LB400, Burkholderia xenovorans LB400, P. xenovorans LB400, Paraburkholderia xenovorans LB400, Pseudomonas LB400, Pseudomonas sp. (strain LB400), Pseudomonas sp. LB400
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