node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Bxe_C0508 | bphC | Bxe_C0508 | Bxe_C1191 | Putative dehydrogenase flavoprotein. | 2,3-Dihydroxybiphenyl-1,2-dioxygenase (BphC); Shows a preference for catechols with groups immediately adjacent to the hydroxyl substituents; Belongs to the extradiol ring-cleavage dioxygenase family. | 0.799 |
bphA1 | bphA2 | Bxe_C1197 | Bxe_C1196 | Biphenyl 2,3-dioxygenase alpha subunit (BphA1); Biphenyl pathway; Citation: J. Bacteriol. 174 (9), 2903-2912 (1992). | Biphenyl 2,3-dioxygenase small subunit (BphA2); The beta subunit may be responsible for the substrate specificity of the enzyme; Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family. | 0.999 |
bphA1 | bphA4 | Bxe_C1197 | Bxe_C1193 | Biphenyl 2,3-dioxygenase alpha subunit (BphA1); Biphenyl pathway; Citation: J. Bacteriol. 174 (9), 2903-2912 (1992). | Biphenyl 2,3-dioxygenase ferredoxin reductase subunit (BphA4); Part of the electron transfer component of biphenyl dioxygenase, transfers electrons from ferredoxin (BphF) to NADH. | 0.821 |
bphA1 | bphB | Bxe_C1197 | Bxe_C1192 | Biphenyl 2,3-dioxygenase alpha subunit (BphA1); Biphenyl pathway; Citation: J. Bacteriol. 174 (9), 2903-2912 (1992). | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase (BphB); Biphenyl pathway; Citation: J. Bacteriol. 174 (9), 2903-2912 (1992); Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.916 |
bphA1 | bphC | Bxe_C1197 | Bxe_C1191 | Biphenyl 2,3-dioxygenase alpha subunit (BphA1); Biphenyl pathway; Citation: J. Bacteriol. 174 (9), 2903-2912 (1992). | 2,3-Dihydroxybiphenyl-1,2-dioxygenase (BphC); Shows a preference for catechols with groups immediately adjacent to the hydroxyl substituents; Belongs to the extradiol ring-cleavage dioxygenase family. | 0.765 |
bphA1 | bphD | Bxe_C1197 | Bxe_C1186 | Biphenyl 2,3-dioxygenase alpha subunit (BphA1); Biphenyl pathway; Citation: J. Bacteriol. 174 (9), 2903-2912 (1992). | 2-hydroxy-6-oxo-6-phenylhexa-2,4- dienoate hydrolase (BphD); Catalyzes an unusual C-C bond hydrolysis of 2-hydroxy-6-oxo- 6-phenylhexa-2,4-dienoic acid (HOPDA) to produce benzoic acid and 2- hydroxy-2,4-pentadienoic acid (HPD); Belongs to the AB hydrolase superfamily. BphD family. | 0.762 |
bphA1 | bphH | Bxe_C1197 | Bxe_C1189 | Biphenyl 2,3-dioxygenase alpha subunit (BphA1); Biphenyl pathway; Citation: J. Bacteriol. 174 (9), 2903-2912 (1992). | 2-hydroxypenta-2,4-dienoate hydratase (BphH); Biphenyl pathway; Citation: J. Bacteriol. 174 (9), 2903-2912 (1992). Gene 144 (1), 9-16 (1994). | 0.451 |
bphA1 | bphI | Bxe_C1197 | Bxe_C1187 | Biphenyl 2,3-dioxygenase alpha subunit (BphA1); Biphenyl pathway; Citation: J. Bacteriol. 174 (9), 2903-2912 (1992). | 4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of both 4-hydroxy-2- oxopentanoate (HOPA) and 4-hydroxy-2-oxohexanoate (HOHA) to pyruvate and acetaldehyde or propanaldehyde, respectively. The aldehydes produced by this reaction are directly channeled from BphI to the dehydrogenase BphJ, ensuring that these toxic aldehydes are sequestered from cellular components. Is involved in the meta-cleavage pathway for the degradation of polychlorinated biphenyls (PCBs). Appears to be stereospecific since it can cleave (4S)-4-hydroxy-2-oxopentanoate but not the (4R) isomer. Al [...] | 0.520 |
bphA1 | bphJ | Bxe_C1197 | Bxe_C1188 | Biphenyl 2,3-dioxygenase alpha subunit (BphA1); Biphenyl pathway; Citation: J. Bacteriol. 174 (9), 2903-2912 (1992). | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde or propanal to acetyl-CoA or propanoyl-CoA, respectively, using NAD(+) and coenzyme A. Displays broad specificity since it can utilize aliphatic aldehydes from two to five carbons in length as substrates; the aldehyde substrates can be directly channeled from the aldolase BphI to the dehydrogenase BphJ. Is the final enzyme in the meta-cleavage pathway for the degradation of polychlorinated biphenyls (PCBs). Is also able to utilize NADP(+) instead of NAD(+). Is not active with succinic semialdehyde or picolinaldehyde a [...] | 0.526 |
bphA2 | bphA1 | Bxe_C1196 | Bxe_C1197 | Biphenyl 2,3-dioxygenase small subunit (BphA2); The beta subunit may be responsible for the substrate specificity of the enzyme; Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family. | Biphenyl 2,3-dioxygenase alpha subunit (BphA1); Biphenyl pathway; Citation: J. Bacteriol. 174 (9), 2903-2912 (1992). | 0.999 |
bphA2 | bphA4 | Bxe_C1196 | Bxe_C1193 | Biphenyl 2,3-dioxygenase small subunit (BphA2); The beta subunit may be responsible for the substrate specificity of the enzyme; Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family. | Biphenyl 2,3-dioxygenase ferredoxin reductase subunit (BphA4); Part of the electron transfer component of biphenyl dioxygenase, transfers electrons from ferredoxin (BphF) to NADH. | 0.882 |
bphA2 | bphB | Bxe_C1196 | Bxe_C1192 | Biphenyl 2,3-dioxygenase small subunit (BphA2); The beta subunit may be responsible for the substrate specificity of the enzyme; Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family. | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase (BphB); Biphenyl pathway; Citation: J. Bacteriol. 174 (9), 2903-2912 (1992); Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.959 |
bphA2 | bphC | Bxe_C1196 | Bxe_C1191 | Biphenyl 2,3-dioxygenase small subunit (BphA2); The beta subunit may be responsible for the substrate specificity of the enzyme; Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family. | 2,3-Dihydroxybiphenyl-1,2-dioxygenase (BphC); Shows a preference for catechols with groups immediately adjacent to the hydroxyl substituents; Belongs to the extradiol ring-cleavage dioxygenase family. | 0.785 |
bphA2 | bphD | Bxe_C1196 | Bxe_C1186 | Biphenyl 2,3-dioxygenase small subunit (BphA2); The beta subunit may be responsible for the substrate specificity of the enzyme; Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family. | 2-hydroxy-6-oxo-6-phenylhexa-2,4- dienoate hydrolase (BphD); Catalyzes an unusual C-C bond hydrolysis of 2-hydroxy-6-oxo- 6-phenylhexa-2,4-dienoic acid (HOPDA) to produce benzoic acid and 2- hydroxy-2,4-pentadienoic acid (HPD); Belongs to the AB hydrolase superfamily. BphD family. | 0.738 |
bphA2 | bphH | Bxe_C1196 | Bxe_C1189 | Biphenyl 2,3-dioxygenase small subunit (BphA2); The beta subunit may be responsible for the substrate specificity of the enzyme; Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family. | 2-hydroxypenta-2,4-dienoate hydratase (BphH); Biphenyl pathway; Citation: J. Bacteriol. 174 (9), 2903-2912 (1992). Gene 144 (1), 9-16 (1994). | 0.454 |
bphA2 | bphI | Bxe_C1196 | Bxe_C1187 | Biphenyl 2,3-dioxygenase small subunit (BphA2); The beta subunit may be responsible for the substrate specificity of the enzyme; Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family. | 4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of both 4-hydroxy-2- oxopentanoate (HOPA) and 4-hydroxy-2-oxohexanoate (HOHA) to pyruvate and acetaldehyde or propanaldehyde, respectively. The aldehydes produced by this reaction are directly channeled from BphI to the dehydrogenase BphJ, ensuring that these toxic aldehydes are sequestered from cellular components. Is involved in the meta-cleavage pathway for the degradation of polychlorinated biphenyls (PCBs). Appears to be stereospecific since it can cleave (4S)-4-hydroxy-2-oxopentanoate but not the (4R) isomer. Al [...] | 0.578 |
bphA2 | bphJ | Bxe_C1196 | Bxe_C1188 | Biphenyl 2,3-dioxygenase small subunit (BphA2); The beta subunit may be responsible for the substrate specificity of the enzyme; Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family. | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde or propanal to acetyl-CoA or propanoyl-CoA, respectively, using NAD(+) and coenzyme A. Displays broad specificity since it can utilize aliphatic aldehydes from two to five carbons in length as substrates; the aldehyde substrates can be directly channeled from the aldolase BphI to the dehydrogenase BphJ. Is the final enzyme in the meta-cleavage pathway for the degradation of polychlorinated biphenyls (PCBs). Is also able to utilize NADP(+) instead of NAD(+). Is not active with succinic semialdehyde or picolinaldehyde a [...] | 0.598 |
bphA4 | bphA1 | Bxe_C1193 | Bxe_C1197 | Biphenyl 2,3-dioxygenase ferredoxin reductase subunit (BphA4); Part of the electron transfer component of biphenyl dioxygenase, transfers electrons from ferredoxin (BphF) to NADH. | Biphenyl 2,3-dioxygenase alpha subunit (BphA1); Biphenyl pathway; Citation: J. Bacteriol. 174 (9), 2903-2912 (1992). | 0.821 |
bphA4 | bphA2 | Bxe_C1193 | Bxe_C1196 | Biphenyl 2,3-dioxygenase ferredoxin reductase subunit (BphA4); Part of the electron transfer component of biphenyl dioxygenase, transfers electrons from ferredoxin (BphF) to NADH. | Biphenyl 2,3-dioxygenase small subunit (BphA2); The beta subunit may be responsible for the substrate specificity of the enzyme; Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family. | 0.882 |
bphA4 | bphB | Bxe_C1193 | Bxe_C1192 | Biphenyl 2,3-dioxygenase ferredoxin reductase subunit (BphA4); Part of the electron transfer component of biphenyl dioxygenase, transfers electrons from ferredoxin (BphF) to NADH. | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase (BphB); Biphenyl pathway; Citation: J. Bacteriol. 174 (9), 2903-2912 (1992); Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.900 |