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glnB protein (Mesorhizobium loti) - STRING interaction network
"glnB" - Nitrogen regulatory protein P-II in Mesorhizobium loti
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Known Interactions
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Predicted Interactions
gene neighborhood
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gene co-occurrence
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textmining
co-expression
protein homology
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glnBNitrogen regulatory protein P-II; In nitrogen-limiting conditions, when the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP. P- II-UMP allows the deadenylation of glutamine synthetase (GS), thus activating the enzyme. Conversely, in nitrogen excess P-II is deuridylated and promotes the adenylation of GS. P-II indirectly controls the transcription of the GS gene (glnA). P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate, the transcriptional activator of glnA. When P-II is uridylylated to P- II-UMP, these events are reversed (By similarity) (112 aa)    
Predicted Functional Partners:
mll4246
AmtB (451 aa)
 
  0.999
glnD
PII uridylyl-transferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen fixation and metabolism (933 aa)
 
  0.997
mll3030
Glutamate synthase (1581 aa)
 
   
  0.974
mll0343
Glutamine synthetase (469 aa)
 
 
  0.966
mlr0397
NirB (380 aa)
   
  0.958
mll0767
Sensor kinase (898 aa)
   
 
  0.933
argB
Acetylglutamate kinase (297 aa)
     
 
  0.852
glnE
Adenylyltransferase; Adenylation and deadenylation of glutamate--ammonia ligase (986 aa)
 
  0.834
mll2385
Sensory histidine kinase (1622 aa)
   
 
  0.792
mll3440
Hypothetical protein (426 aa)
   
 
  0.778
Your Current Organism:
Mesorhizobium loti
NCBI taxonomy Id: 266835
Other names: M. loti, M. loti MAFF303099, Mesorhizobium loti, Mesorhizobium loti MAFF303099, Mesorhizobium loti str. MAFF303099, Mesorhizobium loti strain MAFF303099, Rhizobium loti
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