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mll0663 protein (Mesorhizobium loti) - STRING interaction network
"mll0663" - Endopeptidase Clp ATP-binding protein subunit A in Mesorhizobium loti
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
mll0663Endopeptidase Clp ATP-binding protein subunit A (822 aa)    
Predicted Functional Partners:
clpS1
ATP-dependent Clp protease adaptor protein ClpS; Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (109 aa)
 
 
  0.999
dnaK
DnaK; Acts as a chaperone (638 aa)
   
 
  0.974
clpS2
ATP-dependent Clp protease adaptor; Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (101 aa)
 
 
  0.968
clpP2
ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (209 aa)
   
 
  0.923
dnaJ
DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are r [...] (376 aa)
   
 
  0.914
grpE
GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- dependent interact [...] (210 aa)
   
 
  0.880
mll5617
DnaK (418 aa)
   
 
  0.857
clpX
ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (424 aa)
 
 
  0.857
aat
leucyl/phenylalanyl-tRNA--protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (205 aa)
 
 
 
  0.848
groL2
Molecular chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (542 aa)
   
 
  0.815
Your Current Organism:
Mesorhizobium loti
NCBI taxonomy Id: 266835
Other names: M. loti, M. loti MAFF303099, Mesorhizobium loti, Mesorhizobium loti MAFF303099, Mesorhizobium loti str. MAFF303099, Mesorhizobium loti strain MAFF303099, Rhizobium loti
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