STRINGSTRING
cobQ protein (Mesorhizobium loti) - STRING interaction network
"cobQ" - Cobyric acid synthase in Mesorhizobium loti
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobQCobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (491 aa)    
Predicted Functional Partners:
cobD
CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (324 aa)
 
 
  0.997
mll1306
cob(I)alamin adenosyltransferase (204 aa)
 
 
  0.996
mll1303
CobC (348 aa)
 
 
  0.987
mll1308
Cobinamide kinase (171 aa)
   
  0.982
mlr3485
Hypothetical protein (193 aa)
 
 
  0.982
mlr1381
precorrin-3B C17-methyltransferase (254 aa)
   
  0.978
cobB
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source (439 aa)
   
  0.977
cobT
Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5’-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (336 aa)
 
   
  0.932
mll0563
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (332 aa)
 
   
  0.931
cobS
Cobalamin (5’-phosphate) synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5’-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5’-phosphate (259 aa)
 
   
  0.931
Your Current Organism:
Mesorhizobium loti
NCBI taxonomy Id: 266835
Other names: M. loti, M. loti MAFF303099, Mesorhizobium loti, Mesorhizobium loti MAFF303099, Mesorhizobium loti str. MAFF303099, Mesorhizobium loti strain MAFF303099, Rhizobium loti
Server load: low (7%) [HD]