STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
disAProtein of unknown function DUF147; Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions. (359 aa)    
Predicted Functional Partners:
radA
DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
  
  
 0.956
Krad_0467
Hypothetical protein.
  
     0.712
Krad_1171
PFAM: UvrD/REP helicase; KEGG: art:Arth_2757 UvrD/REP helicase.
   
    0.600
Krad_3968
PFAM: Phosphoesterase HXTX; KEGG: ace:Acel_0391 2',5' RNA ligase.
  
     0.557
Krad_0899
4-diphosphocytidyl-2C-methyl-D-erythritol synthase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
  
    0.475
Krad_3099
PFAM: protein of unknown function DUF1290; KEGG: sma:SAV6979 hypothetical protein.
  
     0.460
Krad_1412
PFAM: peptidase M23B; KEGG: aau:AAur_1502 M23 peptidase domain protein.
     
 0.452
Krad_3100
PFAM: protein of unknown function DUF881; KEGG: sma:SAV6978 hypothetical protein.
  
     0.443
Krad_0898
Transcriptional regulator, CarD family; PFAM: transcription factor CarD; KEGG: sma:SAV3970 putative CarD-like transcriptional regulator.
 
     0.425
Krad_0026
PFAM: protein of unknown function DUF881; KEGG: ace:Acel_0015 protein of unknown function DUF881.
  
     0.421
Your Current Organism:
Kineococcus radiotolerans
NCBI taxonomy Id: 266940
Other names: K. radiotolerans SRS30216 = ATCC BAA-149, Kineococcus radiotolerans ATCC BAA-149, Kineococcus radiotolerans ATCC BAA-149 = SRS30216, Kineococcus radiotolerans SRS30216, Kineococcus radiotolerans SRS30216 = ATCC BAA-149, Kineococcus-like str. SRS30216
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