STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemLTIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class I and II; aminotransferase class-III; KEGG: fal:FRAAL0997 glutamate-1-semialdehyde aminotransferase (aminomutase), PLP-dependent. (448 aa)    
Predicted Functional Partners:
Krad_0620
Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: sma:SAV4742 putative 5-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
 
 0.997
hemA
Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.996
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.969
Krad_0627
PFAM: Phosphoglycerate mutase; KEGG: nca:Noca_0500 phosphoglycerate mutase.
  
    0.960
Krad_0629
PFAM: cytochrome c biogenesis protein transmembrane region; KEGG: nca:Noca_0502 cytochrome c biogenesis protein, transmembrane region.
  
  
 0.942
Krad_0631
PFAM: cytochrome c assembly protein; KEGG: aau:AAur_pTC10173 putative cytochrome biogenesis protein.
 
  
 0.925
Krad_0619
PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: nca:Noca_0496 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase.
 
  
 0.893
Krad_1326
TIGRFAM: uroporphyrin-III C-methyltransferase; siroheme synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: art:Arth_3111 uroporphyrin-III C-methyltransferase.
 
   
 0.892
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.889
Krad_0630
PFAM: ResB family protein; KEGG: aau:AAur_pTC10174 putative cytochrome c biogenesis membrane protein, ResB-like family.
  
  
 0.860
Your Current Organism:
Kineococcus radiotolerans
NCBI taxonomy Id: 266940
Other names: K. radiotolerans SRS30216 = ATCC BAA-149, Kineococcus radiotolerans ATCC BAA-149, Kineococcus radiotolerans ATCC BAA-149 = SRS30216, Kineococcus radiotolerans SRS30216, Kineococcus radiotolerans SRS30216 = ATCC BAA-149, Kineococcus-like str. SRS30216
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