node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Krad_0294 | Krad_1488 | Krad_0294 | Krad_1488 | PFAM: Formamidopyrimidine-DNA glycolase; KEGG: fal:FRAAL5723 endonuclease VIII. | PFAM: Formamidopyrimidine-DNA glycolase; KEGG: sma:SAV2501 putative endonuclease VIII. | 0.911 |
Krad_0294 | coaE | Krad_0294 | Krad_2943 | PFAM: Formamidopyrimidine-DNA glycolase; KEGG: fal:FRAAL5723 endonuclease VIII. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.411 |
Krad_0294 | mutM | Krad_0294 | Krad_1377 | PFAM: Formamidopyrimidine-DNA glycolase; KEGG: fal:FRAAL5723 endonuclease VIII. | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.774 |
Krad_0294 | nth | Krad_0294 | Krad_0422 | PFAM: Formamidopyrimidine-DNA glycolase; KEGG: fal:FRAAL5723 endonuclease VIII. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.525 |
Krad_0294 | polA | Krad_0294 | Krad_2951 | PFAM: Formamidopyrimidine-DNA glycolase; KEGG: fal:FRAAL5723 endonuclease VIII. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.760 |
Krad_0294 | rnc | Krad_0294 | Krad_1376 | PFAM: Formamidopyrimidine-DNA glycolase; KEGG: fal:FRAAL5723 endonuclease VIII. | Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.448 |
Krad_1368 | Krad_1374 | Krad_1368 | Krad_1374 | PFAM: helicase domain protein; nucleic acid binding OB-fold tRNA/helicase-type; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: tfu:Tfu_0646 ATP-dependent DNA helicase RecG. | PFAM: protein of unknown function DUF177; KEGG: nca:Noca_3282 protein of unknown function DUF177. | 0.584 |
Krad_1368 | mutM | Krad_1368 | Krad_1377 | PFAM: helicase domain protein; nucleic acid binding OB-fold tRNA/helicase-type; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: tfu:Tfu_0646 ATP-dependent DNA helicase RecG. | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.593 |
Krad_1368 | nth | Krad_1368 | Krad_0422 | PFAM: helicase domain protein; nucleic acid binding OB-fold tRNA/helicase-type; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: tfu:Tfu_0646 ATP-dependent DNA helicase RecG. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.463 |
Krad_1368 | polA | Krad_1368 | Krad_2951 | PFAM: helicase domain protein; nucleic acid binding OB-fold tRNA/helicase-type; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: tfu:Tfu_0646 ATP-dependent DNA helicase RecG. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.669 |
Krad_1368 | rnc | Krad_1368 | Krad_1376 | PFAM: helicase domain protein; nucleic acid binding OB-fold tRNA/helicase-type; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: tfu:Tfu_0646 ATP-dependent DNA helicase RecG. | Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.531 |
Krad_1368 | rpmF | Krad_1368 | Krad_1375 | PFAM: helicase domain protein; nucleic acid binding OB-fold tRNA/helicase-type; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: tfu:Tfu_0646 ATP-dependent DNA helicase RecG. | TIGRFAM: ribosomal protein L32; PFAM: ribosomal L32p protein; KEGG: art:Arth_2502 ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family. | 0.602 |
Krad_1374 | Krad_1368 | Krad_1374 | Krad_1368 | PFAM: protein of unknown function DUF177; KEGG: nca:Noca_3282 protein of unknown function DUF177. | PFAM: helicase domain protein; nucleic acid binding OB-fold tRNA/helicase-type; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: tfu:Tfu_0646 ATP-dependent DNA helicase RecG. | 0.584 |
Krad_1374 | mutM | Krad_1374 | Krad_1377 | PFAM: protein of unknown function DUF177; KEGG: nca:Noca_3282 protein of unknown function DUF177. | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.654 |
Krad_1374 | rnc | Krad_1374 | Krad_1376 | PFAM: protein of unknown function DUF177; KEGG: nca:Noca_3282 protein of unknown function DUF177. | Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.864 |
Krad_1374 | rpmF | Krad_1374 | Krad_1375 | PFAM: protein of unknown function DUF177; KEGG: nca:Noca_3282 protein of unknown function DUF177. | TIGRFAM: ribosomal protein L32; PFAM: ribosomal L32p protein; KEGG: art:Arth_2502 ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family. | 0.988 |
Krad_1488 | Krad_0294 | Krad_1488 | Krad_0294 | PFAM: Formamidopyrimidine-DNA glycolase; KEGG: sma:SAV2501 putative endonuclease VIII. | PFAM: Formamidopyrimidine-DNA glycolase; KEGG: fal:FRAAL5723 endonuclease VIII. | 0.911 |
Krad_1488 | coaE | Krad_1488 | Krad_2943 | PFAM: Formamidopyrimidine-DNA glycolase; KEGG: sma:SAV2501 putative endonuclease VIII. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.411 |
Krad_1488 | mutM | Krad_1488 | Krad_1377 | PFAM: Formamidopyrimidine-DNA glycolase; KEGG: sma:SAV2501 putative endonuclease VIII. | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.757 |
Krad_1488 | nth | Krad_1488 | Krad_0422 | PFAM: Formamidopyrimidine-DNA glycolase; KEGG: sma:SAV2501 putative endonuclease VIII. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.525 |