STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RSc3436Conserved hypothetical protein; Miscellaneous; hypothetical/global homology. (667 aa)    
Predicted Functional Partners:
dnaJ
Probable chaperone protein dnaj; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions betwee [...]
  
 0.957
RSc0639
Probable heat shock protein.
   
 0.902
hscA
Probable chaperone protein hsca homolog; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
   
 0.902
dnaK
Probable chaperone protein dnak (heat shock protein 70) (heat shock 70 kdaprotein) (hsp70); Acts as a chaperone.; Belongs to the heat shock protein 70 family.
   
 0.902
hscC
Probable chaperone transmembrane protein; Belongs to the heat shock protein 70 family.
   
 0.902
RSp0216
Putative type III effector protein (serine/threonine-protein kinase).
    
 0.886
mopA
Probable 60 kda chaperonin (protein cpn60) (groel protein); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 
 0.806
ppiB
Probable peptidyl-prolyl cis-trans isomerase b (ppiase b) (rotamase b)(cypb protein); PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
  
 0.791
ppiA
Probable peptidyl-prolyl cis-trans isomerase a (ppiase a)(rotamase a)(cyph) signal peptide protein; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
  
 0.791
RSc3437
Putative galactose mutarotase-like protein.
       0.773
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
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