node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
argS | asnS | MMOB1240 | MMOB5070 | arginyl-tRNA synthetase; COG0018; expression validated by proteogenomic mapping: 25 unique peptides covering 37.7% of sequence. | asparaginyl-tRNA synthetase; COG0017; expression validated by proteogenomic mapping: 34 unique peptides covering 60.4% of sequence. | 0.917 |
argS | gltX | MMOB1240 | MMOB0050 | arginyl-tRNA synthetase; COG0018; expression validated by proteogenomic mapping: 25 unique peptides covering 37.7% of sequence. | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | 0.991 |
argS | ileS | MMOB1240 | MMOB4070 | arginyl-tRNA synthetase; COG0018; expression validated by proteogenomic mapping: 25 unique peptides covering 37.7% of sequence. | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | 0.992 |
argS | leuS | MMOB1240 | MMOB5390 | arginyl-tRNA synthetase; COG0018; expression validated by proteogenomic mapping: 25 unique peptides covering 37.7% of sequence. | leucyl-tRNA synthetase; COG0495; expression validated by proteogenomic mapping: 18 unique peptides covering 37.5% of sequence. | 0.945 |
argS | lysS | MMOB1240 | MMOB0440 | arginyl-tRNA synthetase; COG0018; expression validated by proteogenomic mapping: 25 unique peptides covering 37.7% of sequence. | lysyl-tRNA synthetase; COG1190; expression validated by proteogenomic mapping: 39 unique peptides covering 60.6% of sequence; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.882 |
argS | metS | MMOB1240 | MMOB3150 | arginyl-tRNA synthetase; COG0018; expression validated by proteogenomic mapping: 25 unique peptides covering 37.7% of sequence. | methionyl-tRNA synthetase; COG0143; expression validated by proteogenomic mapping: 11 unique peptides covering 30.3% of sequence. | 0.984 |
argS | pheT | MMOB1240 | MMOB5160 | arginyl-tRNA synthetase; COG0018; expression validated by proteogenomic mapping: 25 unique peptides covering 37.7% of sequence. | phenylalanyl-tRNA synthetase beta chain; COG0072; expression validated by proteogenomic mapping: 17 unique peptides covering 31.3% of sequence; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.806 |
argS | proRS | MMOB1240 | MMOB1440 | arginyl-tRNA synthetase; COG0018; expression validated by proteogenomic mapping: 25 unique peptides covering 37.7% of sequence. | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). | 0.962 |
asnS | argS | MMOB5070 | MMOB1240 | asparaginyl-tRNA synthetase; COG0017; expression validated by proteogenomic mapping: 34 unique peptides covering 60.4% of sequence. | arginyl-tRNA synthetase; COG0018; expression validated by proteogenomic mapping: 25 unique peptides covering 37.7% of sequence. | 0.917 |
asnS | gltX | MMOB5070 | MMOB0050 | asparaginyl-tRNA synthetase; COG0017; expression validated by proteogenomic mapping: 34 unique peptides covering 60.4% of sequence. | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | 0.946 |
asnS | ileS | MMOB5070 | MMOB4070 | asparaginyl-tRNA synthetase; COG0017; expression validated by proteogenomic mapping: 34 unique peptides covering 60.4% of sequence. | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | 0.965 |
asnS | leuS | MMOB5070 | MMOB5390 | asparaginyl-tRNA synthetase; COG0017; expression validated by proteogenomic mapping: 34 unique peptides covering 60.4% of sequence. | leucyl-tRNA synthetase; COG0495; expression validated by proteogenomic mapping: 18 unique peptides covering 37.5% of sequence. | 0.850 |
asnS | lysS | MMOB5070 | MMOB0440 | asparaginyl-tRNA synthetase; COG0017; expression validated by proteogenomic mapping: 34 unique peptides covering 60.4% of sequence. | lysyl-tRNA synthetase; COG1190; expression validated by proteogenomic mapping: 39 unique peptides covering 60.6% of sequence; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.740 |
asnS | metS | MMOB5070 | MMOB3150 | asparaginyl-tRNA synthetase; COG0017; expression validated by proteogenomic mapping: 34 unique peptides covering 60.4% of sequence. | methionyl-tRNA synthetase; COG0143; expression validated by proteogenomic mapping: 11 unique peptides covering 30.3% of sequence. | 0.972 |
asnS | pheT | MMOB5070 | MMOB5160 | asparaginyl-tRNA synthetase; COG0017; expression validated by proteogenomic mapping: 34 unique peptides covering 60.4% of sequence. | phenylalanyl-tRNA synthetase beta chain; COG0072; expression validated by proteogenomic mapping: 17 unique peptides covering 31.3% of sequence; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.645 |
asnS | proRS | MMOB5070 | MMOB1440 | asparaginyl-tRNA synthetase; COG0017; expression validated by proteogenomic mapping: 34 unique peptides covering 60.4% of sequence. | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). | 0.924 |
asnS | topA | MMOB5070 | MMOB0820 | asparaginyl-tRNA synthetase; COG0017; expression validated by proteogenomic mapping: 34 unique peptides covering 60.4% of sequence. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.844 |
gltX | argS | MMOB0050 | MMOB1240 | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | arginyl-tRNA synthetase; COG0018; expression validated by proteogenomic mapping: 25 unique peptides covering 37.7% of sequence. | 0.991 |
gltX | asnS | MMOB0050 | MMOB5070 | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | asparaginyl-tRNA synthetase; COG0017; expression validated by proteogenomic mapping: 34 unique peptides covering 60.4% of sequence. | 0.946 |
gltX | ileS | MMOB0050 | MMOB4070 | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | 0.994 |