node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MMOB4170 | folD | MMOB4170 | MMOB1600 | Expressed protein; COG0739; expression validated by proteogenomic mapping: 26 unique peptides covering 53.6% of sequence. | Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.454 |
MMOB4170 | pdhD-2 | MMOB4170 | MMOB5800 | Expressed protein; COG0739; expression validated by proteogenomic mapping: 26 unique peptides covering 53.6% of sequence. | Pyruvate dehydrogenase E3 component dihydrolipoamide dehydrogenase; COG1249; expression validated by proteogenomic mapping: 88 unique peptides covering 75% of sequence. | 0.588 |
MMOB4170 | pepQ | MMOB4170 | MMOB5500 | Expressed protein; COG0739; expression validated by proteogenomic mapping: 26 unique peptides covering 53.6% of sequence. | XAA-PRO dipeptidase; COG0006; expression validated by proteogenomic mapping: 26 unique peptides covering 63.6% of sequence. | 0.618 |
MMOB5520 | efp | MMOB5520 | MMOB5510 | Hypothetical protein; Expression not validated. | Elongation factor p; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | 0.773 |
MMOB5520 | nfo | MMOB5520 | MMOB5480 | Hypothetical protein; Expression not validated. | Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. | 0.514 |
MMOB5520 | pepQ | MMOB5520 | MMOB5500 | Hypothetical protein; Expression not validated. | XAA-PRO dipeptidase; COG0006; expression validated by proteogenomic mapping: 26 unique peptides covering 63.6% of sequence. | 0.773 |
MMOB5520 | rpmG | MMOB5520 | MMOB5490 | Hypothetical protein; Expression not validated. | 50S ribosomal protein L33; COG0267; expression validated by proteogenomic mapping: 3 unique peptides covering 44% of sequence; Belongs to the bacterial ribosomal protein bL33 family. | 0.701 |
MMOB5520 | tktA | MMOB5520 | MMOB5530 | Hypothetical protein; Expression not validated. | Transketolase; COG0021; expression validated by proteogenomic mapping: 83 unique peptides covering 74.1% of sequence; Belongs to the transketolase family. | 0.768 |
MMOB5520 | tyrS | MMOB5520 | MMOB5470 | Hypothetical protein; Expression not validated. | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. | 0.416 |
efp | MMOB5520 | MMOB5510 | MMOB5520 | Elongation factor p; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | Hypothetical protein; Expression not validated. | 0.773 |
efp | nfo | MMOB5510 | MMOB5480 | Elongation factor p; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. | 0.606 |
efp | pepQ | MMOB5510 | MMOB5500 | Elongation factor p; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | XAA-PRO dipeptidase; COG0006; expression validated by proteogenomic mapping: 26 unique peptides covering 63.6% of sequence. | 0.865 |
efp | rpmG | MMOB5510 | MMOB5490 | Elongation factor p; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | 50S ribosomal protein L33; COG0267; expression validated by proteogenomic mapping: 3 unique peptides covering 44% of sequence; Belongs to the bacterial ribosomal protein bL33 family. | 0.997 |
efp | tktA | MMOB5510 | MMOB5530 | Elongation factor p; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | Transketolase; COG0021; expression validated by proteogenomic mapping: 83 unique peptides covering 74.1% of sequence; Belongs to the transketolase family. | 0.857 |
efp | topA | MMOB5510 | MMOB0820 | Elongation factor p; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.545 |
efp | tyrS | MMOB5510 | MMOB5470 | Elongation factor p; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. | 0.614 |
folD | MMOB4170 | MMOB1600 | MMOB4170 | Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Expressed protein; COG0739; expression validated by proteogenomic mapping: 26 unique peptides covering 53.6% of sequence. | 0.454 |
folD | pdhD-2 | MMOB1600 | MMOB5800 | Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Pyruvate dehydrogenase E3 component dihydrolipoamide dehydrogenase; COG1249; expression validated by proteogenomic mapping: 88 unique peptides covering 75% of sequence. | 0.511 |
folD | pepQ | MMOB1600 | MMOB5500 | Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | XAA-PRO dipeptidase; COG0006; expression validated by proteogenomic mapping: 26 unique peptides covering 63.6% of sequence. | 0.752 |
nfo | MMOB5520 | MMOB5480 | MMOB5520 | Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. | Hypothetical protein; Expression not validated. | 0.514 |