STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (201 aa)    
Predicted Functional Partners:
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
 
 0.975
hpt
Hypoxanthine-guanine phosphoribosyltransferase; COG0634; expression validated by proteogenomic mapping: 13 unique peptides covering 52.7% of sequence; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
    
 0.960
pyk
Pyruvate kinase; COG0469; expression validated by proteogenomic mapping: 72 unique peptides covering 78.9% of sequence; Belongs to the pyruvate kinase family.
  
 
 0.925
nrdA
Ribonucleotide reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
    
 0.914
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 
 0.914
MMOB5580
Phosphoprotein ser/thr phosphatase; COG0631; expression validated by proteogenomic mapping: 24 unique peptides covering 63.1% of sequence.
   
   0.839
sps1-2
Serine/threonine protein kinase; COG0515; expression validated by proteogenomic mapping: 27 unique peptides covering 51.8% of sequence.
      0.831
cls
Cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
    
  0.805
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
   
 
 0.782
ribA
Riboflavin biosynthesis protein; COG0807; expression validated by proteogenomic mapping: 9 unique peptides covering 20.4% of sequence.
  
 
 0.729
Your Current Organism:
Mycoplasma mobile
NCBI taxonomy Id: 267748
Other names: M. mobile 163K, Mycoplasma mobile 163K, Mycoplasma mobile str. 163K, Mycoplasma mobile strain 163K
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.