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mhpC protein (Burkholderia vietnamiensis) - STRING interaction network
"mhpC" - 2-hydroxy-6-oxononadienedioate/2-hydroxy-6-oxononatrienedioate hydrolase in Burkholderia vietnamiensis
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query proteins and first shell of interactors
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second shell of interactors
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some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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mhpC2-hydroxy-6-oxononadienedioate/2-hydroxy-6-oxononatrienedioate hydrolase; Catalyzes the cleavage of the C5-C6 bond of 2-hydroxy-6- oxononadienedioate and 2-hydroxy-6-oxononatrienedioate, a dienol ring fission product of the bacterial meta-cleavage pathway for degradation of phenylpropionic acid (288 aa)    
Predicted Functional Partners:
mhpB
2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase; Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively; Belongs to the LigB/MhpB extradiol dioxygenase family (317 aa)
 
   
    0.989
mhpD
2-keto-4-pentenoate hydratase; Catalyzes the conversion of 2-hydroxypentadienoic acid (enolic form of 2-oxopent-4-enoate) to 4-hydroxy-2-ketopentanoic acid; Belongs to the hydratase/decarboxylase family. MhpD subfamily (262 aa)
 
   
  0.984
ABO58330.1
4-hydroxy-2-oxovalerate aldolase 1; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (339 aa)
 
     
  0.906
ABO58331.1
Acetaldehyde dehydrogenase 1; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds (315 aa)
 
     
  0.894
mhpA1
3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase 1; Catalyzes the insertion of one atom of molecular oxygen into position 2 of the phenyl ring of 3-(3- hydroxyphenyl)propionate (3-HPP) and hydroxycinnamic acid (3HCI) (615 aa)
 
     
  0.861
ABO58329.1
PFAM- General substrate transporter; major facilitator superfamily MFS_1; KEGG- bxe-Bxe_B2324 major facilitator superfamily (MFS) aromatic acid transporter (MhpT) (417 aa)
 
 
      0.854
ABO58335.1
PFAM- regulatory proteins, IclR; KEGG- bxe-Bxe_B2330 transcriptional regulator, IclR family (MhpR) (270 aa)
 
          0.761
ABO60478.1
4-hydroxy-2-oxovalerate aldolase 2; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (348 aa)
 
     
  0.665
ABO60477.1
Acetaldehyde dehydrogenase 2; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds (303 aa)
 
     
  0.645
mhpA2
3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase 2; Catalyzes the insertion of one atom of molecular oxygen into position 2 of the phenyl ring of 3-(3- hydroxyphenyl)propionate (3-HPP) and hydroxycinnamic acid (3HCI) (546 aa)
 
     
  0.577
Your Current Organism:
Burkholderia vietnamiensis
NCBI taxonomy Id: 269482
Other names: B. vietnamiensis G4, Burkholderia vietnamiensis, Burkholderia vietnamiensis G4, Burkholderia vietnamiensis str. G4, Burkholderia vietnamiensis strain G4
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