STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ecaj_0145Phosphate ABC transporter membrane protein 1, PhoT family; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (374 aa)    
Predicted Functional Partners:
Ecaj_0150
Phosphate ABC transporter substrate-binding protein, PhoT family; TC 3.A.1.7.1.
 
 
 0.999
Ecaj_0536
Phosphate ABC transporter membrane protein 2, PhoT family; TC 3.A.1.7.1.
 
0.999
Ecaj_0578
Phosphate ABC transporter ATP-binding protein, PhoT family; TC 3.A.1.7.1; Belongs to the ABC transporter superfamily.
 
 
 0.999
Ecaj_0144
Glutamine synthetase, catalytic domain.
     
 0.839
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
       0.606
lolD
ABC transporter; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
     
 0.496
Ecaj_0112
Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
      
 0.487
Ecaj_0817
Response regulator receiver: C terminal.
     
 0.457
Your Current Organism:
Ehrlichia canis
NCBI taxonomy Id: 269484
Other names: E. canis str. Jake, Ehrlichia canis Jake, Ehrlichia canis str. Jake, Ehrlichia canis strain Jake
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.