node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ecaj_0706 | dcd | Ecaj_0706 | Ecaj_0707 | Conserved hypothetical protein. | dCTP deaminase; Catalyzes the deamination of dCTP to dUTP. | 0.418 |
Ecaj_0706 | polA | Ecaj_0706 | Ecaj_0048 | Conserved hypothetical protein. | DNA polymerase, family A; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.507 |
Ecaj_0708 | dcd | Ecaj_0708 | Ecaj_0707 | ABC transporter; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. | dCTP deaminase; Catalyzes the deamination of dCTP to dUTP. | 0.448 |
coaD | dcd | Ecaj_0329 | Ecaj_0707 | Co enzyme A biosynthesis protein:Cytidyl transferase-related domain; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | dCTP deaminase; Catalyzes the deamination of dCTP to dUTP. | 0.448 |
dcd | Ecaj_0706 | Ecaj_0707 | Ecaj_0706 | dCTP deaminase; Catalyzes the deamination of dCTP to dUTP. | Conserved hypothetical protein. | 0.418 |
dcd | Ecaj_0708 | Ecaj_0707 | Ecaj_0708 | dCTP deaminase; Catalyzes the deamination of dCTP to dUTP. | ABC transporter; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. | 0.448 |
dcd | coaD | Ecaj_0707 | Ecaj_0329 | dCTP deaminase; Catalyzes the deamination of dCTP to dUTP. | Co enzyme A biosynthesis protein:Cytidyl transferase-related domain; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.448 |
dcd | dut | Ecaj_0707 | Ecaj_0527 | dCTP deaminase; Catalyzes the deamination of dCTP to dUTP. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.925 |
dcd | ndk | Ecaj_0707 | Ecaj_0893 | dCTP deaminase; Catalyzes the deamination of dCTP to dUTP. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.923 |
dcd | polA | Ecaj_0707 | Ecaj_0048 | dCTP deaminase; Catalyzes the deamination of dCTP to dUTP. | DNA polymerase, family A; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.527 |
dcd | pyrE | Ecaj_0707 | Ecaj_0886 | dCTP deaminase; Catalyzes the deamination of dCTP to dUTP. | Orotate phosphoribosyl transferase, Thermus type; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.487 |
dcd | pyrG | Ecaj_0707 | Ecaj_0114 | dCTP deaminase; Catalyzes the deamination of dCTP to dUTP. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.915 |
dcd | tmk | Ecaj_0707 | Ecaj_0780 | dCTP deaminase; Catalyzes the deamination of dCTP to dUTP. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.466 |
dut | dcd | Ecaj_0527 | Ecaj_0707 | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | dCTP deaminase; Catalyzes the deamination of dCTP to dUTP. | 0.925 |
dut | ndk | Ecaj_0527 | Ecaj_0893 | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.940 |
dut | polA | Ecaj_0527 | Ecaj_0048 | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | DNA polymerase, family A; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.679 |
dut | tmk | Ecaj_0527 | Ecaj_0780 | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.950 |
ndk | dcd | Ecaj_0893 | Ecaj_0707 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | dCTP deaminase; Catalyzes the deamination of dCTP to dUTP. | 0.923 |
ndk | dut | Ecaj_0893 | Ecaj_0527 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.940 |
ndk | pyrG | Ecaj_0893 | Ecaj_0114 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.942 |