node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Rru_A0554 | Rru_A1252 | Rru_A0554 | Rru_A1252 | Rh-like protein/ammonium transporter. | L-glutamine synthetase. | 0.431 |
Rru_A0554 | Rru_A1677 | Rru_A0554 | Rru_A1677 | Rh-like protein/ammonium transporter. | Signal transduction histidine kinase, nitrogen specific, NtrB. | 0.703 |
Rru_A0554 | Rru_A2079 | Rru_A0554 | Rru_A2079 | Rh-like protein/ammonium transporter. | L-glutamine synthetase. | 0.431 |
Rru_A0554 | Rru_A2086 | Rru_A0554 | Rru_A2086 | Rh-like protein/ammonium transporter. | L-glutamine synthetase. | 0.431 |
Rru_A0554 | glnB | Rru_A0554 | Rru_A2085 | Rh-like protein/ammonium transporter. | Nitrogen regulatory protein P-II (GlnB, GlnK); P-II indirectly controls the transcription of the glutamine synthetase gene (glnA). P-II prevents NR-II-catalyzed conversion of NR- I to NR-I-phosphate, the transcriptional activator of glnA. When P-II is uridylylated to P-II-UMP, these events are reversed. When the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP, which causes the deadenylation of glutamine synthetase, so activating the enzyme; Belongs to the P(II) protein family. | 0.996 |
Rru_A0554 | glnD | Rru_A0554 | Rru_A3539 | Rh-like protein/ammonium transporter. | GlnB (protein PII) uridylyltransferase, GlnD; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen fixation and metabolism. | 0.435 |
Rru_A0554 | nifH-2 | Rru_A0554 | Rru_A1010 | Rh-like protein/ammonium transporter. | Nitrogenase iron protein subunit NifH; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family. | 0.439 |
Rru_A1008 | glnB | Rru_A1008 | Rru_A2085 | ADP-ribosyl-(dinitrogen reductase) hydrolase. | Nitrogen regulatory protein P-II (GlnB, GlnK); P-II indirectly controls the transcription of the glutamine synthetase gene (glnA). P-II prevents NR-II-catalyzed conversion of NR- I to NR-I-phosphate, the transcriptional activator of glnA. When P-II is uridylylated to P-II-UMP, these events are reversed. When the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP, which causes the deadenylation of glutamine synthetase, so activating the enzyme; Belongs to the P(II) protein family. | 0.788 |
Rru_A1129 | Rru_A1252 | Rru_A1129 | Rru_A1252 | Ammonium transporter. | L-glutamine synthetase. | 0.435 |
Rru_A1129 | Rru_A1677 | Rru_A1129 | Rru_A1677 | Ammonium transporter. | Signal transduction histidine kinase, nitrogen specific, NtrB. | 0.703 |
Rru_A1129 | Rru_A2079 | Rru_A1129 | Rru_A2079 | Ammonium transporter. | L-glutamine synthetase. | 0.435 |
Rru_A1129 | Rru_A2086 | Rru_A1129 | Rru_A2086 | Ammonium transporter. | L-glutamine synthetase. | 0.554 |
Rru_A1129 | glnB | Rru_A1129 | Rru_A2085 | Ammonium transporter. | Nitrogen regulatory protein P-II (GlnB, GlnK); P-II indirectly controls the transcription of the glutamine synthetase gene (glnA). P-II prevents NR-II-catalyzed conversion of NR- I to NR-I-phosphate, the transcriptional activator of glnA. When P-II is uridylylated to P-II-UMP, these events are reversed. When the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP, which causes the deadenylation of glutamine synthetase, so activating the enzyme; Belongs to the P(II) protein family. | 0.997 |
Rru_A1129 | glnD | Rru_A1129 | Rru_A3539 | Ammonium transporter. | GlnB (protein PII) uridylyltransferase, GlnD; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen fixation and metabolism. | 0.799 |
Rru_A1129 | nifH-2 | Rru_A1129 | Rru_A1010 | Ammonium transporter. | Nitrogenase iron protein subunit NifH; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family. | 0.700 |
Rru_A1252 | Rru_A0554 | Rru_A1252 | Rru_A0554 | L-glutamine synthetase. | Rh-like protein/ammonium transporter. | 0.431 |
Rru_A1252 | Rru_A1129 | Rru_A1252 | Rru_A1129 | L-glutamine synthetase. | Ammonium transporter. | 0.435 |
Rru_A1252 | Rru_A2079 | Rru_A1252 | Rru_A2079 | L-glutamine synthetase. | L-glutamine synthetase. | 0.805 |
Rru_A1252 | Rru_A2086 | Rru_A1252 | Rru_A2086 | L-glutamine synthetase. | L-glutamine synthetase. | 0.844 |
Rru_A1252 | glnB | Rru_A1252 | Rru_A2085 | L-glutamine synthetase. | Nitrogen regulatory protein P-II (GlnB, GlnK); P-II indirectly controls the transcription of the glutamine synthetase gene (glnA). P-II prevents NR-II-catalyzed conversion of NR- I to NR-I-phosphate, the transcriptional activator of glnA. When P-II is uridylylated to P-II-UMP, these events are reversed. When the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP, which causes the deadenylation of glutamine synthetase, so activating the enzyme; Belongs to the P(II) protein family. | 0.793 |