node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Rru_A0471 | Rru_A0732 | Rru_A0471 | Rru_A0732 | Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape. | DNA repair protein RadC; Belongs to the UPF0758 family. | 0.870 |
Rru_A0471 | Rru_A2768 | Rru_A0471 | Rru_A2768 | Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape. | Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 0.619 |
Rru_A0732 | Rru_A0471 | Rru_A0732 | Rru_A0471 | DNA repair protein RadC; Belongs to the UPF0758 family. | Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape. | 0.870 |
Rru_A0732 | Rru_A2768 | Rru_A0732 | Rru_A2768 | DNA repair protein RadC; Belongs to the UPF0758 family. | Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 0.798 |
Rru_A2767 | Rru_A2768 | Rru_A2767 | Rru_A2768 | Ribonuclease G (RNase G). | Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 0.868 |
Rru_A2767 | Rru_A2769 | Rru_A2767 | Rru_A2769 | Ribonuclease G (RNase G). | Protein tyrosine phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | 0.530 |
Rru_A2767 | Rru_A2770 | Rru_A2767 | Rru_A2770 | Ribonuclease G (RNase G). | Uncharacterized conserved protein UCP032146; Belongs to the UPF0262 family. | 0.529 |
Rru_A2767 | hisD | Rru_A2767 | Rru_A2771 | Ribonuclease G (RNase G). | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.522 |
Rru_A2767 | hisG | Rru_A2767 | Rru_A2772 | Ribonuclease G (RNase G). | ATP phosphoribosyltransferase (homohexameric); Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | 0.522 |
Rru_A2767 | yacG | Rru_A2767 | Rru_A2766 | Ribonuclease G (RNase G). | Protein of unknown function DUF329; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase. | 0.537 |
Rru_A2768 | Rru_A0471 | Rru_A2768 | Rru_A0471 | Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape. | 0.619 |
Rru_A2768 | Rru_A0732 | Rru_A2768 | Rru_A0732 | Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | DNA repair protein RadC; Belongs to the UPF0758 family. | 0.798 |
Rru_A2768 | Rru_A2767 | Rru_A2768 | Rru_A2767 | Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Ribonuclease G (RNase G). | 0.868 |
Rru_A2768 | Rru_A2769 | Rru_A2768 | Rru_A2769 | Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Protein tyrosine phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | 0.596 |
Rru_A2768 | Rru_A2770 | Rru_A2768 | Rru_A2770 | Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Uncharacterized conserved protein UCP032146; Belongs to the UPF0262 family. | 0.588 |
Rru_A2768 | coaE | Rru_A2768 | Rru_A3612 | Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.498 |
Rru_A2768 | hisD | Rru_A2768 | Rru_A2771 | Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.667 |
Rru_A2768 | hisG | Rru_A2768 | Rru_A2772 | Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | ATP phosphoribosyltransferase (homohexameric); Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | 0.635 |
Rru_A2768 | purA | Rru_A2768 | Rru_A1106 | Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.528 |
Rru_A2768 | yacG | Rru_A2768 | Rru_A2766 | Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Protein of unknown function DUF329; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase. | 0.579 |