STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pckGPhosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (620 aa)    
Predicted Functional Partners:
nifJ
Pyruvate-ferredoxin (flavodoxin) oxidoreductase; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin, which reduces nitrogenase.
  
 
 0.993
Rru_A1121
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
   
 
 0.972
Rru_A2721
2-oxoglutarate synthase, alpha subunit.
   
 
 0.972
Rru_A2465
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.937
mdh
Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
    
 0.936
Rru_A1600
Citrate synthase; Belongs to the citrate synthase family.
   
 
 0.936
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
     
 0.925
Rru_A2956
Pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family.
     
 0.924
Rru_A1320
Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit; Beta subunit of the biotin-dependent malonate decarboxylase multienzyme complex (EC 7.2.4.4). Acts as an integral membrane-bound carboxybiotin protein decarboxylase by releasing the carboxyl group of the carboxylated biotin carrier MADF. The free energy of the decarboxylation reaction is used to pump Na(+) out of the cell.
     
  0.900
Rru_A3673
Glutaconyl-CoA decarboxylase.
     
  0.900
Your Current Organism:
Rhodospirillum rubrum
NCBI taxonomy Id: 269796
Other names: R. rubrum ATCC 11170, Rhodospirillum rubrum ATCC 11170, Rhodospirillum rubrum S1, Rhodospirillum rubrum str. ATCC 11170, Rhodospirillum rubrum strain ATCC 11170
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