STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
psmAProteasome, subunit-alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (249 aa)    
Predicted Functional Partners:
psmB
Proteasome endopeptidase complex, beta component, Threonine peptidase, MEROPS family T01A; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
 
 
0.999
pan
Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...]
 
 0.956
AAZ69383.1
Proteasome-activating nucleotidase; Belongs to the AAA ATPase family.
 
 0.951
AAZ71937.1
Proteasome Rpn11 subunit JAMM motif, Metallo peptidase, MEROPS family M67B.
   
 0.950
AAZ71417.1
Conserved hypothetical protein.
 
  
 0.911
rpl40e
LSU ribosomal protein L40E; Belongs to the eukaryotic ribosomal protein eL40 family.
   
 0.889
AAZ69882.1
Cell division control protein 48.
 
 0.847
AAZ71245.1
Cell division control protein 48 AAA family protein.
 
 0.847
rpl15e
LSU ribosomal protein L15E; Belongs to the eukaryotic ribosomal protein eL15 family.
 
  
 0.847
AAZ71009.1
Cell division cycle protein.
 
 0.843
Your Current Organism:
Methanosarcina barkeri Fusaro
NCBI taxonomy Id: 269797
Other names: M. barkeri str. Fusaro, Methanosarcina barkeri DSM 804, Methanosarcina barkeri str. Fusaro, Methanosarcina barkeri strain Fusaro
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.