node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CHU_1323 | moaE | CHU_1323 | CHU_1324 | Hypothetical protein. | Molybdopterin synthase subunit MoaE. | 0.999 |
CHU_1323 | thiF | CHU_1323 | CHU_0245 | Hypothetical protein. | Thiamine biosynthesis protein (HesA/MoeB/ThiF family protein). | 0.994 |
CHU_1323 | thiG | CHU_1323 | CHU_0243 | Hypothetical protein. | Thiazole-phosphate synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.923 |
dxs-2 | thiG | CHU_3643 | CHU_0243 | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | Thiazole-phosphate synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.921 |
moaE | CHU_1323 | CHU_1324 | CHU_1323 | Molybdopterin synthase subunit MoaE. | Hypothetical protein. | 0.999 |
moaE | thiF | CHU_1324 | CHU_0245 | Molybdopterin synthase subunit MoaE. | Thiamine biosynthesis protein (HesA/MoeB/ThiF family protein). | 0.968 |
moaE | thiG | CHU_1324 | CHU_0243 | Molybdopterin synthase subunit MoaE. | Thiazole-phosphate synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.698 |
thiC | thiD | CHU_0240 | CHU_0241 | Hydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | Phosphomethylpyrimidine kinase. | 0.993 |
thiC | thiE | CHU_0240 | CHU_0242 | Hydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.924 |
thiC | thiE-2 | CHU_0240 | CHU_0246 | Hydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | Thiamine-phosphate diphosphorylase. | 0.868 |
thiC | thiF | CHU_0240 | CHU_0245 | Hydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | Thiamine biosynthesis protein (HesA/MoeB/ThiF family protein). | 0.881 |
thiC | thiG | CHU_0240 | CHU_0243 | Hydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | Thiazole-phosphate synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.973 |
thiC | thiH | CHU_0240 | CHU_0244 | Hydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | Tyrosine lyase ThiH. | 0.967 |
thiC | thiS | CHU_0240 | CHU_0239 | Hydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | Sulfur carrier protein ThiS. | 0.961 |
thiD | thiC | CHU_0241 | CHU_0240 | Phosphomethylpyrimidine kinase. | Hydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | 0.993 |
thiD | thiE | CHU_0241 | CHU_0242 | Phosphomethylpyrimidine kinase. | Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.999 |
thiD | thiE-2 | CHU_0241 | CHU_0246 | Phosphomethylpyrimidine kinase. | Thiamine-phosphate diphosphorylase. | 0.991 |
thiD | thiF | CHU_0241 | CHU_0245 | Phosphomethylpyrimidine kinase. | Thiamine biosynthesis protein (HesA/MoeB/ThiF family protein). | 0.853 |
thiD | thiG | CHU_0241 | CHU_0243 | Phosphomethylpyrimidine kinase. | Thiazole-phosphate synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.975 |
thiD | thiH | CHU_0241 | CHU_0244 | Phosphomethylpyrimidine kinase. | Tyrosine lyase ThiH. | 0.907 |