node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CHU_0011 | kmo | CHU_0011 | CHU_3380 | Fatty acid hydroxylase. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. | 0.451 |
CHU_0469 | kmo | CHU_0469 | CHU_3380 | Sterol desaturase-related protein. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. | 0.451 |
CHU_1409 | CHU_3433 | CHU_1409 | CHU_3433 | Tryptophan 2,3-dioxygenase apoenzyme. | Conserved hypothetical protein. | 0.581 |
CHU_1409 | iscS-2 | CHU_1409 | CHU_3381 | Tryptophan 2,3-dioxygenase apoenzyme. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.997 |
CHU_1409 | kmo | CHU_1409 | CHU_3380 | Tryptophan 2,3-dioxygenase apoenzyme. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. | 0.897 |
CHU_1409 | nbaC | CHU_1409 | CHU_3382 | Tryptophan 2,3-dioxygenase apoenzyme. | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. | 0.661 |
CHU_1699 | kmo | CHU_1699 | CHU_3380 | Sterol desaturase family protein. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. | 0.451 |
CHU_2247 | kmo | CHU_2247 | CHU_3380 | Conserved hypothetical protein. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. | 0.514 |
CHU_3383 | iscS-2 | CHU_3383 | CHU_3381 | Hypothetical protein. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.485 |
CHU_3383 | kmo | CHU_3383 | CHU_3380 | Hypothetical protein. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. | 0.485 |
CHU_3383 | nbaC | CHU_3383 | CHU_3382 | Hypothetical protein. | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. | 0.497 |
CHU_3433 | CHU_1409 | CHU_3433 | CHU_1409 | Conserved hypothetical protein. | Tryptophan 2,3-dioxygenase apoenzyme. | 0.581 |
CHU_3433 | iscS-2 | CHU_3433 | CHU_3381 | Conserved hypothetical protein. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.596 |
CHU_3433 | kmo | CHU_3433 | CHU_3380 | Conserved hypothetical protein. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. | 0.660 |
CHU_3433 | nbaC | CHU_3433 | CHU_3382 | Conserved hypothetical protein. | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. | 0.718 |
idi | kmo | CHU_0674 | CHU_3380 | Isopentenyl-diphosphate delta-isomerase. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. | 0.559 |
iscS-2 | CHU_1409 | CHU_3381 | CHU_1409 | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | Tryptophan 2,3-dioxygenase apoenzyme. | 0.997 |
iscS-2 | CHU_3383 | CHU_3381 | CHU_3383 | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | Hypothetical protein. | 0.485 |
iscS-2 | CHU_3433 | CHU_3381 | CHU_3433 | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | Conserved hypothetical protein. | 0.596 |
iscS-2 | kmo | CHU_3381 | CHU_3380 | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. | 0.999 |