STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fumCFumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (462 aa)    
Predicted Functional Partners:
sdhA
Succinate dehydrogenase subunit A.
 
 0.992
maeB
Allosteric NADP-dependent malic enzyme.
  
 
 0.974
fumB
Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.969
frdB
Succinate dehydrogenase, iron-sulfur subunit (fumarate reductase, iron-sulfur subunit).
  
 0.968
mdh
Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 0.967
gltA
Citrate synthase; Belongs to the citrate synthase family.
   
 0.918
CHU_2472
Succinate dehydrogenase subunit C.
     
  0.900
yneI
Aldehyde dehydrogenase.
    
 0.845
argH
Argininosuccinate lyase.
   
 
0.827
aspB
Aminotransferase.
    
 0.819
Your Current Organism:
Cytophaga hutchinsonii
NCBI taxonomy Id: 269798
Other names: C. hutchinsonii ATCC 33406, Cytophaga hutchinsonii ATCC 33406, Cytophaga hutchinsonii str. ATCC 33406, Cytophaga hutchinsonii strain ATCC 33406
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.