STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ctaBProtoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (271 aa)    
Predicted Functional Partners:
coxB
Cytochrome c; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
 
 
 0.999
coxA
Cytochrome c; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
 
 0.998
coxC
Oxidase, coo3-type, subunit III.
 
 
 0.998
coxD
Oxidase, coo3-type, subunit IV.
 
  
  0.993
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
   
 
 0.930
sco
Oxidase, coo3-type, synthesis factor.
 
  
 0.923
Gmet_0015
Radical SAM domain iron-sulfur cluster-binding oxidoreductase.
     
  0.900
nuoBCD
NADH dehydrogenase I, B/C/D subunits; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 20 kDa subunit family. In the C-terminal section; belongs to the complex I 49 [...]
   
  
 0.874
Gmet_0037
Hypothetical protein.
  
  
 0.802
sucA
2-oxoglutarate dehydrogenase, E1 protein.
  
  
 0.601
Your Current Organism:
Geobacter metallireducens
NCBI taxonomy Id: 269799
Other names: G. metallireducens GS-15, Geobacter metallireducens GS-15, Geobacter metallireducens str. GS-15, Geobacter metallireducens strain GS-15
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.