node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Gmet_1630 | pyrF | Gmet_1630 | Gmet_1355 | HAD superfamily hydrolase. | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.904 |
Gmet_1630 | pyrH | Gmet_1630 | Gmet_1252 | HAD superfamily hydrolase. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.900 |
Gmet_1630 | pyrR | Gmet_1630 | Gmet_1768 | HAD superfamily hydrolase. | Pyrimidine operon regulator and uracil phosphoribosyltransferase PyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. | 0.900 |
Gmet_1630 | surE | Gmet_1630 | Gmet_1419 | HAD superfamily hydrolase. | Nucleoside 3'/5'-monophosphate phosphatase and short-chain exopolyphosphatase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.914 |
carA | pyrB | Gmet_1771 | Gmet_1769 | Carbamyl-phosphate synthase, small subunit; Belongs to the CarA family. | Aspartate carbamyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
carA | pyrC | Gmet_1771 | Gmet_1770 | Carbamyl-phosphate synthase, small subunit; Belongs to the CarA family. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.997 |
carA | pyrD | Gmet_1771 | Gmet_1841 | Carbamyl-phosphate synthase, small subunit; Belongs to the CarA family. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. | 0.925 |
carA | pyrE | Gmet_1771 | Gmet_1938 | Carbamyl-phosphate synthase, small subunit; Belongs to the CarA family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.902 |
carA | pyrF | Gmet_1771 | Gmet_1355 | Carbamyl-phosphate synthase, small subunit; Belongs to the CarA family. | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.904 |
carA | pyrK | Gmet_1771 | Gmet_1842 | Carbamyl-phosphate synthase, small subunit; Belongs to the CarA family. | Dihydroorotate dehydrogenase, electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). | 0.838 |
carA | pyrR | Gmet_1771 | Gmet_1768 | Carbamyl-phosphate synthase, small subunit; Belongs to the CarA family. | Pyrimidine operon regulator and uracil phosphoribosyltransferase PyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. | 0.908 |
pyrB | carA | Gmet_1769 | Gmet_1771 | Aspartate carbamyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Carbamyl-phosphate synthase, small subunit; Belongs to the CarA family. | 0.999 |
pyrB | pyrC | Gmet_1769 | Gmet_1770 | Aspartate carbamyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.999 |
pyrB | pyrD | Gmet_1769 | Gmet_1841 | Aspartate carbamyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. | 0.938 |
pyrB | pyrE | Gmet_1769 | Gmet_1938 | Aspartate carbamyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.915 |
pyrB | pyrF | Gmet_1769 | Gmet_1355 | Aspartate carbamyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.939 |
pyrB | pyrH | Gmet_1769 | Gmet_1252 | Aspartate carbamyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.495 |
pyrB | pyrK | Gmet_1769 | Gmet_1842 | Aspartate carbamyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Dihydroorotate dehydrogenase, electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). | 0.875 |
pyrB | pyrR | Gmet_1769 | Gmet_1768 | Aspartate carbamyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Pyrimidine operon regulator and uracil phosphoribosyltransferase PyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. | 0.997 |
pyrC | carA | Gmet_1770 | Gmet_1771 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Carbamyl-phosphate synthase, small subunit; Belongs to the CarA family. | 0.997 |