STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (434 aa)    
Predicted Functional Partners:
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.997
hemL
Glutamate-1-semialdehyde 2,1-aminomutase.
 
 0.990
hemD
Uroporphyrinogen III C2,C7-methyltransferase and uroporphyrinogen III synthase.
 
  
 0.982
gltX
glutamyl-tRNA synthetase, non-discriminating; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
     
 0.928
cysG
Precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase, putative.
 
   
 0.889
hemB
Porphobilinogen synthase; Belongs to the ALAD family.
 
  
 0.879
Gmet_3232
ResC/HemX-like cytochrome c; Biogenesis membrane protein.
 
  
 0.856
por
Pyruvate:ferredoxin/flavodoxin oxidoreductase.
   
   0.792
flaG
Flagellar protein FlaG.
   
   0.633
fliL
Flagellar basal body-associated protein FliL; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.
   
   0.589
Your Current Organism:
Geobacter metallireducens
NCBI taxonomy Id: 269799
Other names: G. metallireducens GS-15, Geobacter metallireducens GS-15, Geobacter metallireducens str. GS-15, Geobacter metallireducens strain GS-15
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