node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Gmet_2911 | birA | Gmet_2911 | Gmet_1987 | Oxidoreductase, flavin-binding protein. | Biotin operon repressor and biotin--acetyl-CoA carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.494 |
Gmet_2911 | nadA | Gmet_2911 | Gmet_3544 | Oxidoreductase, flavin-binding protein. | Quinolinate synthetase complex, subunit A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | 0.994 |
Gmet_2911 | nadB | Gmet_2911 | Gmet_1954 | Oxidoreductase, flavin-binding protein. | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. | 0.923 |
Gmet_2911 | nadC | Gmet_2911 | Gmet_1988 | Oxidoreductase, flavin-binding protein. | Quinolinate phosphoribosyltransferase, decarboxylating; Belongs to the NadC/ModD family. | 0.920 |
bioB | birA | Gmet_1582 | Gmet_1987 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Biotin operon repressor and biotin--acetyl-CoA carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.959 |
bioB | nadA | Gmet_1582 | Gmet_3544 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Quinolinate synthetase complex, subunit A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | 0.572 |
bioB | ribD | Gmet_1582 | Gmet_1624 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.489 |
birA | Gmet_2911 | Gmet_1987 | Gmet_2911 | Biotin operon repressor and biotin--acetyl-CoA carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Oxidoreductase, flavin-binding protein. | 0.494 |
birA | bioB | Gmet_1987 | Gmet_1582 | Biotin operon repressor and biotin--acetyl-CoA carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.959 |
birA | nadA | Gmet_1987 | Gmet_3544 | Biotin operon repressor and biotin--acetyl-CoA carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Quinolinate synthetase complex, subunit A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | 0.557 |
birA | nadB | Gmet_1987 | Gmet_1954 | Biotin operon repressor and biotin--acetyl-CoA carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. | 0.494 |
birA | nadC | Gmet_1987 | Gmet_1988 | Biotin operon repressor and biotin--acetyl-CoA carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Quinolinate phosphoribosyltransferase, decarboxylating; Belongs to the NadC/ModD family. | 0.891 |
birA | ribD | Gmet_1987 | Gmet_1624 | Biotin operon repressor and biotin--acetyl-CoA carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.768 |
cysE | nadA | Gmet_0870 | Gmet_3544 | Serine O-acetyltransferase. | Quinolinate synthetase complex, subunit A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | 0.814 |
gmk | nadA | Gmet_2327 | Gmet_3544 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Quinolinate synthetase complex, subunit A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | 0.745 |
gmk | ribD | Gmet_2327 | Gmet_1624 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.600 |
nadA | Gmet_2911 | Gmet_3544 | Gmet_2911 | Quinolinate synthetase complex, subunit A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | Oxidoreductase, flavin-binding protein. | 0.994 |
nadA | bioB | Gmet_3544 | Gmet_1582 | Quinolinate synthetase complex, subunit A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.572 |
nadA | birA | Gmet_3544 | Gmet_1987 | Quinolinate synthetase complex, subunit A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | Biotin operon repressor and biotin--acetyl-CoA carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.557 |
nadA | cysE | Gmet_3544 | Gmet_0870 | Quinolinate synthetase complex, subunit A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | Serine O-acetyltransferase. | 0.814 |