node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Tfu_0071 | Tfu_1796 | Tfu_0071 | Tfu_1796 | Conserved hypothetical protein. | Putative proteasome component. | 0.559 |
Tfu_0071 | arc | Tfu_0071 | Tfu_1809 | Conserved hypothetical protein. | Vesicle-fusing ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 0.772 |
Tfu_0071 | prcA | Tfu_0071 | Tfu_1789 | Conserved hypothetical protein. | Putative 20S proteasome alpha-subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family. | 0.997 |
Tfu_0071 | prcB | Tfu_0071 | Tfu_1790 | Conserved hypothetical protein. | Bacterial proteasome, beta component. Threonine peptidase. MEROPS family T01B; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family. | 0.919 |
Tfu_0071 | pup | Tfu_0071 | Tfu_1791 | Conserved hypothetical protein. | Conserved hypothetical protein; Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation. Belongs to the prokaryotic ubiquitin-like protein family. | 0.712 |
Tfu_1061 | Tfu_1796 | Tfu_1061 | Tfu_1796 | Conserved hypothetical protein. | Putative proteasome component. | 0.509 |
Tfu_1061 | arc | Tfu_1061 | Tfu_1809 | Conserved hypothetical protein. | Vesicle-fusing ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 0.610 |
Tfu_1397 | Tfu_1765 | Tfu_1397 | Tfu_1765 | Regulatory protein, MerR. | Helicase, C-terminal:DEAD/DEAH box helicase, N-terminal. | 0.407 |
Tfu_1397 | Tfu_1796 | Tfu_1397 | Tfu_1796 | Regulatory protein, MerR. | Putative proteasome component. | 0.491 |
Tfu_1397 | Tfu_1965 | Tfu_1397 | Tfu_1965 | Regulatory protein, MerR. | Conserved hypothetical protein. | 0.618 |
Tfu_1765 | Tfu_1397 | Tfu_1765 | Tfu_1397 | Helicase, C-terminal:DEAD/DEAH box helicase, N-terminal. | Regulatory protein, MerR. | 0.407 |
Tfu_1765 | Tfu_1796 | Tfu_1765 | Tfu_1796 | Helicase, C-terminal:DEAD/DEAH box helicase, N-terminal. | Putative proteasome component. | 0.450 |
Tfu_1765 | arc | Tfu_1765 | Tfu_1809 | Helicase, C-terminal:DEAD/DEAH box helicase, N-terminal. | Vesicle-fusing ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 0.500 |
Tfu_1765 | prcB | Tfu_1765 | Tfu_1790 | Helicase, C-terminal:DEAD/DEAH box helicase, N-terminal. | Bacterial proteasome, beta component. Threonine peptidase. MEROPS family T01B; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family. | 0.400 |
Tfu_1796 | Tfu_0071 | Tfu_1796 | Tfu_0071 | Putative proteasome component. | Conserved hypothetical protein. | 0.559 |
Tfu_1796 | Tfu_1061 | Tfu_1796 | Tfu_1061 | Putative proteasome component. | Conserved hypothetical protein. | 0.509 |
Tfu_1796 | Tfu_1397 | Tfu_1796 | Tfu_1397 | Putative proteasome component. | Regulatory protein, MerR. | 0.491 |
Tfu_1796 | Tfu_1765 | Tfu_1796 | Tfu_1765 | Putative proteasome component. | Helicase, C-terminal:DEAD/DEAH box helicase, N-terminal. | 0.450 |
Tfu_1796 | Tfu_1816 | Tfu_1796 | Tfu_1816 | Putative proteasome component. | Conserved hypothetical protein. | 0.471 |
Tfu_1796 | Tfu_1965 | Tfu_1796 | Tfu_1965 | Putative proteasome component. | Conserved hypothetical protein. | 0.544 |