node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Tfu_0456 | Tfu_0853 | Tfu_0456 | Tfu_0853 | Undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of only one isopentenyl pyrophosphate (IPP) unit in the cis configuration to E-geranyl diphosphate (E-GPP) generating the 15 carbon product (2Z,6E)-farnesyl diphosphate (Z-FPP or EZ-FPP). Only geranyl diphosphate (GPP) can be used as isoprenyl acceptor. | Undecaprenyl pyrophosphate synthetase; Catalyzes the synthesis of Z,E-mixed prenyl diphosphates by a condensation of isopentenyl diphosphate to an allylic diphosphate. It shows a large substrate specificity accepting dimethylallyl diphosphate (DMAPP), GPP, E,Efarnesyl diphosphate (FPP), E,E,E-geranylgeranyl diphosphate (GGPP), neryl diphosphate (Z-GPP), and (2Z,6E)-farnesyl diphosphate (Z,E-FPP) as allylic substrates. The enzyme exhibits the highest activity when Z,E-FPP is employed as an allylic substrate. The major product is dodecaprenyl diphosphate (C60) under every allylic substra [...] | 0.915 |
Tfu_0456 | murD | Tfu_0456 | Tfu_1108 | Undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of only one isopentenyl pyrophosphate (IPP) unit in the cis configuration to E-geranyl diphosphate (E-GPP) generating the 15 carbon product (2Z,6E)-farnesyl diphosphate (Z-FPP or EZ-FPP). Only geranyl diphosphate (GPP) can be used as isoprenyl acceptor. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.514 |
Tfu_0456 | pheT | Tfu_0456 | Tfu_2060 | Undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of only one isopentenyl pyrophosphate (IPP) unit in the cis configuration to E-geranyl diphosphate (E-GPP) generating the 15 carbon product (2Z,6E)-farnesyl diphosphate (Z-FPP or EZ-FPP). Only geranyl diphosphate (GPP) can be used as isoprenyl acceptor. | phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.653 |
Tfu_0456 | uppP | Tfu_0456 | Tfu_1838 | Undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of only one isopentenyl pyrophosphate (IPP) unit in the cis configuration to E-geranyl diphosphate (E-GPP) generating the 15 carbon product (2Z,6E)-farnesyl diphosphate (Z-FPP or EZ-FPP). Only geranyl diphosphate (GPP) can be used as isoprenyl acceptor. | Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.557 |
Tfu_0853 | Tfu_0456 | Tfu_0853 | Tfu_0456 | Undecaprenyl pyrophosphate synthetase; Catalyzes the synthesis of Z,E-mixed prenyl diphosphates by a condensation of isopentenyl diphosphate to an allylic diphosphate. It shows a large substrate specificity accepting dimethylallyl diphosphate (DMAPP), GPP, E,Efarnesyl diphosphate (FPP), E,E,E-geranylgeranyl diphosphate (GGPP), neryl diphosphate (Z-GPP), and (2Z,6E)-farnesyl diphosphate (Z,E-FPP) as allylic substrates. The enzyme exhibits the highest activity when Z,E-FPP is employed as an allylic substrate. The major product is dodecaprenyl diphosphate (C60) under every allylic substra [...] | Undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of only one isopentenyl pyrophosphate (IPP) unit in the cis configuration to E-geranyl diphosphate (E-GPP) generating the 15 carbon product (2Z,6E)-farnesyl diphosphate (Z-FPP or EZ-FPP). Only geranyl diphosphate (GPP) can be used as isoprenyl acceptor. | 0.915 |
Tfu_0853 | mraY | Tfu_0853 | Tfu_1107 | Undecaprenyl pyrophosphate synthetase; Catalyzes the synthesis of Z,E-mixed prenyl diphosphates by a condensation of isopentenyl diphosphate to an allylic diphosphate. It shows a large substrate specificity accepting dimethylallyl diphosphate (DMAPP), GPP, E,Efarnesyl diphosphate (FPP), E,E,E-geranylgeranyl diphosphate (GGPP), neryl diphosphate (Z-GPP), and (2Z,6E)-farnesyl diphosphate (Z,E-FPP) as allylic substrates. The enzyme exhibits the highest activity when Z,E-FPP is employed as an allylic substrate. The major product is dodecaprenyl diphosphate (C60) under every allylic substra [...] | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.438 |
Tfu_0853 | murD | Tfu_0853 | Tfu_1108 | Undecaprenyl pyrophosphate synthetase; Catalyzes the synthesis of Z,E-mixed prenyl diphosphates by a condensation of isopentenyl diphosphate to an allylic diphosphate. It shows a large substrate specificity accepting dimethylallyl diphosphate (DMAPP), GPP, E,Efarnesyl diphosphate (FPP), E,E,E-geranylgeranyl diphosphate (GGPP), neryl diphosphate (Z-GPP), and (2Z,6E)-farnesyl diphosphate (Z,E-FPP) as allylic substrates. The enzyme exhibits the highest activity when Z,E-FPP is employed as an allylic substrate. The major product is dodecaprenyl diphosphate (C60) under every allylic substra [...] | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.497 |
Tfu_0853 | pheT | Tfu_0853 | Tfu_2060 | Undecaprenyl pyrophosphate synthetase; Catalyzes the synthesis of Z,E-mixed prenyl diphosphates by a condensation of isopentenyl diphosphate to an allylic diphosphate. It shows a large substrate specificity accepting dimethylallyl diphosphate (DMAPP), GPP, E,Efarnesyl diphosphate (FPP), E,E,E-geranylgeranyl diphosphate (GGPP), neryl diphosphate (Z-GPP), and (2Z,6E)-farnesyl diphosphate (Z,E-FPP) as allylic substrates. The enzyme exhibits the highest activity when Z,E-FPP is employed as an allylic substrate. The major product is dodecaprenyl diphosphate (C60) under every allylic substra [...] | phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.596 |
Tfu_0853 | uppP | Tfu_0853 | Tfu_1838 | Undecaprenyl pyrophosphate synthetase; Catalyzes the synthesis of Z,E-mixed prenyl diphosphates by a condensation of isopentenyl diphosphate to an allylic diphosphate. It shows a large substrate specificity accepting dimethylallyl diphosphate (DMAPP), GPP, E,Efarnesyl diphosphate (FPP), E,E,E-geranylgeranyl diphosphate (GGPP), neryl diphosphate (Z-GPP), and (2Z,6E)-farnesyl diphosphate (Z,E-FPP) as allylic substrates. The enzyme exhibits the highest activity when Z,E-FPP is employed as an allylic substrate. The major product is dodecaprenyl diphosphate (C60) under every allylic substra [...] | Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.558 |
Tfu_1835 | Tfu_1836 | Tfu_1835 | Tfu_1836 | Conserved hypothetical protein. | Conserved hypothetical protein. | 0.945 |
Tfu_1835 | Tfu_1837 | Tfu_1835 | Tfu_1837 | Conserved hypothetical protein. | Putative phosphatase. | 0.897 |
Tfu_1835 | Tfu_1839 | Tfu_1835 | Tfu_1839 | Conserved hypothetical protein. | Putative oxidoreductase. | 0.554 |
Tfu_1835 | uppP | Tfu_1835 | Tfu_1838 | Conserved hypothetical protein. | Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.637 |
Tfu_1836 | Tfu_1835 | Tfu_1836 | Tfu_1835 | Conserved hypothetical protein. | Conserved hypothetical protein. | 0.945 |
Tfu_1836 | Tfu_1837 | Tfu_1836 | Tfu_1837 | Conserved hypothetical protein. | Putative phosphatase. | 0.892 |
Tfu_1836 | Tfu_1839 | Tfu_1836 | Tfu_1839 | Conserved hypothetical protein. | Putative oxidoreductase. | 0.547 |
Tfu_1836 | uppP | Tfu_1836 | Tfu_1838 | Conserved hypothetical protein. | Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.681 |
Tfu_1837 | Tfu_1835 | Tfu_1837 | Tfu_1835 | Putative phosphatase. | Conserved hypothetical protein. | 0.897 |
Tfu_1837 | Tfu_1836 | Tfu_1837 | Tfu_1836 | Putative phosphatase. | Conserved hypothetical protein. | 0.892 |
Tfu_1837 | Tfu_1839 | Tfu_1837 | Tfu_1839 | Putative phosphatase. | Putative oxidoreductase. | 0.629 |