STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metE5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (759 aa)    
Predicted Functional Partners:
CHK_2126
5,10-methylenetetrahydrofolate reductase; Homolog of homocysteine-binding domain.
 
 0.998
CHK_1168
Adenosylhomocysteinase.
 
 
 0.984
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
 0.982
CHK_2720
5-methyltetrahydrofolate--homocysteine methyltransferase.
  
 
 0.930
CHK_0845
Homoserine dehydrogenase.
  
 
 0.898
metG
Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
    
 0.895
CHK_1346
Aspartate aminotransferase.
    
 0.842
CHK_3085
Aspartate aminotransferase.
   
 
 0.813
CHK_2127
5-methyltetrahydrofolate--homocysteine methyltransferase.
  
 
 0.785
CHK_0840
O-succinylhomoserine sulfhydrylase.
  
 
 0.763
Your Current Organism:
Catabacter hongkongensis
NCBI taxonomy Id: 270498
Other names: C. hongkongensis, CCUG 54229, Catabacter hongkongensis Lau et al. 2014, JCM 17853, strain HKU16
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.