STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YjeATranslation elongation factor P Lys34:lysine transferase. (299 aa)    
Predicted Functional Partners:
efp
Translation elongation factor P; Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation; Belongs to the elongation factor P family.
 
 
 
 0.896
kamA
Lysyl-lysine 2,3-aminomutase.
 
  
 0.823
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
       0.603
SAM66846.1
FIG074102: hypothetical protein.
       0.531
ilvN
Acetolactate synthase small subunit.
       0.531
ilvB
Acetolactate synthase large subunit.
       0.531
fldA
Flavodoxin 2; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family.
 
      0.430
Your Current Organism:
Cardiobacterium hominis
NCBI taxonomy Id: 2718
Other names: ATCC 15826, C. hominis, CCUG 2711, CIP 70.70, DSM 8339, LMG 3916, LMG:3916, NCTC 10426
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