node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APE_0550 | APE_2336a | APE_0550 | APE_2336a | Conserved hypothetical protein. | Conserved hypothetical protein; Belongs to the UPF0147 family. | 0.459 |
APE_0550 | albA | APE_0550 | APE_1823 | Conserved hypothetical protein. | DNA-binding protein Alba; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes (By similarity); Belongs to the histone-like Alba family. | 0.594 |
APE_0550 | dnaG | APE_0550 | APE_2096.1 | Conserved hypothetical protein. | Exosome complex RNA helicase DnaG homologue; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | 0.697 |
APE_0550 | pcn2 | APE_0550 | APE_2182 | Conserved hypothetical protein. | DNA polymerase sliding clamp B1; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family. | 0.454 |
APE_1322b | albA | APE_1322b | APE_1823 | Hypothetical protein. | DNA-binding protein Alba; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes (By similarity); Belongs to the histone-like Alba family. | 0.785 |
APE_1322b | creN7 | APE_1322b | APE_0450a | Hypothetical protein. | Hypothetical protein; A probable chromatin protein, binds double-strand DNA without sequence specificity. Constrains negative DNA supercoils. Belongs to the Cren7 family. | 0.785 |
APE_1832 | albA | APE_1832 | APE_1823 | Acylamino-acid-releasing enzyme. | DNA-binding protein Alba; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes (By similarity); Belongs to the histone-like Alba family. | 0.785 |
APE_2336a | APE_0550 | APE_2336a | APE_0550 | Conserved hypothetical protein; Belongs to the UPF0147 family. | Conserved hypothetical protein. | 0.459 |
APE_2336a | albA | APE_2336a | APE_1823 | Conserved hypothetical protein; Belongs to the UPF0147 family. | DNA-binding protein Alba; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes (By similarity); Belongs to the histone-like Alba family. | 0.547 |
APE_2336a | vapC3 | APE_2336a | APE_1102 | Conserved hypothetical protein; Belongs to the UPF0147 family. | Conserved hypothetical protein; Toxic component of a type II toxin-antitoxin (TA) system. An RNase; Belongs to the PINc/VapC protein family. | 0.556 |
adkA | albA | APE_0981.1 | APE_1823 | Adenylate kinase; ATP-AMP transphosphorylase; Belongs to the archaeal adenylate kinase family. | DNA-binding protein Alba; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes (By similarity); Belongs to the histone-like Alba family. | 0.598 |
adkA | vapC3 | APE_0981.1 | APE_1102 | Adenylate kinase; ATP-AMP transphosphorylase; Belongs to the archaeal adenylate kinase family. | Conserved hypothetical protein; Toxic component of a type II toxin-antitoxin (TA) system. An RNase; Belongs to the PINc/VapC protein family. | 0.519 |
albA | APE_0550 | APE_1823 | APE_0550 | DNA-binding protein Alba; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes (By similarity); Belongs to the histone-like Alba family. | Conserved hypothetical protein. | 0.594 |
albA | APE_1322b | APE_1823 | APE_1322b | DNA-binding protein Alba; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes (By similarity); Belongs to the histone-like Alba family. | Hypothetical protein. | 0.785 |
albA | APE_1832 | APE_1823 | APE_1832 | DNA-binding protein Alba; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes (By similarity); Belongs to the histone-like Alba family. | Acylamino-acid-releasing enzyme. | 0.785 |
albA | APE_2336a | APE_1823 | APE_2336a | DNA-binding protein Alba; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes (By similarity); Belongs to the histone-like Alba family. | Conserved hypothetical protein; Belongs to the UPF0147 family. | 0.547 |
albA | adkA | APE_1823 | APE_0981.1 | DNA-binding protein Alba; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes (By similarity); Belongs to the histone-like Alba family. | Adenylate kinase; ATP-AMP transphosphorylase; Belongs to the archaeal adenylate kinase family. | 0.598 |
albA | creN7 | APE_1823 | APE_0450a | DNA-binding protein Alba; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes (By similarity); Belongs to the histone-like Alba family. | Hypothetical protein; A probable chromatin protein, binds double-strand DNA without sequence specificity. Constrains negative DNA supercoils. Belongs to the Cren7 family. | 0.809 |
albA | dnaG | APE_1823 | APE_2096.1 | DNA-binding protein Alba; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes (By similarity); Belongs to the histone-like Alba family. | Exosome complex RNA helicase DnaG homologue; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | 0.572 |
albA | fen | APE_1823 | APE_0115.1 | DNA-binding protein Alba; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes (By similarity); Belongs to the histone-like Alba family. | Flap structure-specific endonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair [...] | 0.568 |