STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spoIIEStage II sporulation protein E; BH0078. (830 aa)    
Predicted Functional Partners:
BH0080
Serine/threonine-protein kinase.
 
 
 0.980
spoIIGA
Protease (processing of pro-sigma-E to active sigma-E); Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR.
  
  
 0.960
BH0079
BH0079; unknown conserved protein.
 
  
 0.940
spoIIR
Stage II sporulation protein R; BH3773; required for processing of pro-sigma-E.
  
   
 0.883
spoIIAB
Anti-sigma F factor (stage II sporulation protein AB); Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
  
 0.837
spoIIP
Stage II sporulation protein P; BH1903; required for dissolution of the septal cell wall.
  
   
 0.817
spoIIIAG
Mutants block sporulation after engulfment; BH2791.
  
   
 0.798
spoIIID
Transcriptional regulator of sigma-E- and sigma-K-dependent; BH3740.
  
   
 0.787
spoIIAA
Anti-sigma F factor antagonist (stage II sporulation protein AA); BH1536; Belongs to the anti-sigma-factor antagonist family.
  
  
 0.784
BH0075
BH0075; unknown conserved protein in bacilli.
 
     0.780
Your Current Organism:
Bacillus halodurans
NCBI taxonomy Id: 272558
Other names: B. halodurans C-125, Bacillus halodurans C-125, Bacillus halodurans str. C-125, Bacillus halodurans strain C-125
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.