node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BH0832 | BH2971 | gene:10726706 | gene:10728881 | BH0832; unknown conserved protein in others. | BH2971; unknown conserved protein. | 0.655 |
BH0832 | rsbT | gene:10726706 | gene:10726378 | BH0832; unknown conserved protein in others. | Positive regulator of sigma-B activity (switch protein/serine-threonine kinase); BH0525. | 0.814 |
BH0832 | rsbU | gene:10726706 | gene:10726379 | BH0832; unknown conserved protein in others. | Indirect positive regulator of sigma-B activity (serine phosphatase); BH0526. | 0.704 |
BH0832 | rsbW | gene:10726706 | gene:10726381 | BH0832; unknown conserved protein in others. | Negative regulator of sigma-B activity (switch protein/serine kinase, anti-sigma factor); Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B). | 0.814 |
BH0832 | rsbX | gene:10726706 | gene:10726383 | BH0832; unknown conserved protein in others. | Indirect negative regulator of sigma-B activity (serine phosphatase); BH0530. | 0.704 |
BH0832 | spoIIAB | gene:10726706 | gene:10727435 | BH0832; unknown conserved protein in others. | Anti-sigma F factor (stage II sporulation protein AB); Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.814 |
BH2971 | BH0832 | gene:10728881 | gene:10726706 | BH2971; unknown conserved protein. | BH0832; unknown conserved protein in others. | 0.655 |
BH2971 | rsbR | gene:10728881 | gene:10726376 | BH2971; unknown conserved protein. | Positive regulator of sigma-B activity; BH0523. | 0.655 |
BH2971 | rsbS | gene:10728881 | gene:10726377 | BH2971; unknown conserved protein. | Negative regulator of sigma-B activity (antagonist of RsbT); BH0524. | 0.655 |
BH2971 | rsbT | gene:10728881 | gene:10726378 | BH2971; unknown conserved protein. | Positive regulator of sigma-B activity (switch protein/serine-threonine kinase); BH0525. | 0.747 |
BH2971 | rsbU | gene:10728881 | gene:10726379 | BH2971; unknown conserved protein. | Indirect positive regulator of sigma-B activity (serine phosphatase); BH0526. | 0.743 |
BH2971 | rsbV | gene:10728881 | gene:10726380 | BH2971; unknown conserved protein. | Positive regulator of sigma-B activity (anti-anti-sigma factor); BH0527; Belongs to the anti-sigma-factor antagonist family. | 0.655 |
BH2971 | rsbW | gene:10728881 | gene:10726381 | BH2971; unknown conserved protein. | Negative regulator of sigma-B activity (switch protein/serine kinase, anti-sigma factor); Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B). | 0.756 |
BH2971 | rsbX | gene:10728881 | gene:10726383 | BH2971; unknown conserved protein. | Indirect negative regulator of sigma-B activity (serine phosphatase); BH0530. | 0.743 |
BH2971 | spoIIAB | gene:10728881 | gene:10727435 | BH2971; unknown conserved protein. | Anti-sigma F factor (stage II sporulation protein AB); Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.747 |
rsbR | BH2971 | gene:10726376 | gene:10728881 | Positive regulator of sigma-B activity; BH0523. | BH2971; unknown conserved protein. | 0.655 |
rsbR | rsbS | gene:10726376 | gene:10726377 | Positive regulator of sigma-B activity; BH0523. | Negative regulator of sigma-B activity (antagonist of RsbT); BH0524. | 0.992 |
rsbR | rsbT | gene:10726376 | gene:10726378 | Positive regulator of sigma-B activity; BH0523. | Positive regulator of sigma-B activity (switch protein/serine-threonine kinase); BH0525. | 0.998 |
rsbR | rsbU | gene:10726376 | gene:10726379 | Positive regulator of sigma-B activity; BH0523. | Indirect positive regulator of sigma-B activity (serine phosphatase); BH0526. | 0.985 |
rsbR | rsbV | gene:10726376 | gene:10726380 | Positive regulator of sigma-B activity; BH0523. | Positive regulator of sigma-B activity (anti-anti-sigma factor); BH0527; Belongs to the anti-sigma-factor antagonist family. | 0.861 |