STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rsbXIndirect negative regulator of sigma-B activity (serine phosphatase); BH0530. (206 aa)    
Predicted Functional Partners:
rsbS
Negative regulator of sigma-B activity (antagonist of RsbT); BH0524.
 
 
 0.988
rsbR
Positive regulator of sigma-B activity; BH0523.
 
 
 0.987
rsbT
Positive regulator of sigma-B activity (switch protein/serine-threonine kinase); BH0525.
 
 
 0.987
rsbW
Negative regulator of sigma-B activity (switch protein/serine kinase, anti-sigma factor); Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).
 
 
 0.983
rsbV
Positive regulator of sigma-B activity (anti-anti-sigma factor); BH0527; Belongs to the anti-sigma-factor antagonist family.
  
 
 0.974
rsbU
Indirect positive regulator of sigma-B activity (serine phosphatase); BH0526.
 
   
 0.945
sigB
RNA polymerase general stress sigma factor(sigma B); BH0529; Belongs to the sigma-70 factor family.
 
 
 0.898
sigF
RNA polymerase sigma-F factor (stage II sporulation protein AC); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 0.872
BH2971
BH2971; unknown conserved protein.
  
  
 0.743
BH0832
BH0832; unknown conserved protein in others.
  
 
 0.704
Your Current Organism:
Bacillus halodurans
NCBI taxonomy Id: 272558
Other names: B. halodurans C-125, Bacillus halodurans C-125, Bacillus halodurans str. C-125, Bacillus halodurans strain C-125
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.