STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BH2309Allantoinase; Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring; Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family. (438 aa)    
Predicted Functional Partners:
pyrB
Aspartate carbamoyltransferase; BH2539; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
 0.998
pyrAB
Carbamoyl-phosphate synthetase (catalytic subunit); BH2536; Belongs to the CarB family.
 
 0.971
BH0761
N-carbamyl-L-amino acid amidohydrolase.
 
 
 0.970
BH0759
Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
 
 
 0.969
carB
Arginine specific carbamoyl-phosphate synthase large chain; BH2895; Belongs to the CarB family.
 
 0.967
carA
Arginine specific carbamoyl-phosphate synthase small chain; BH2896.
  
 0.965
pyrAA
Carbamoyl-phosphate synthetase (glutaminase subunit); BH2537.
 
  
 0.960
BH0758
BH0758; unknown conserved protein.
 
  
 0.947
pyrD
Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
 
 
 0.906
pyrR
Transcriptional attenuation of the pyrimidine operon/uracil phosphoribosyl transferase; Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes. Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
 
 
 0.876
Your Current Organism:
Bacillus halodurans
NCBI taxonomy Id: 272558
Other names: B. halodurans C-125, Bacillus halodurans C-125, Bacillus halodurans str. C-125, Bacillus halodurans strain C-125
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