node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BH1495 | BH2941 | gene:10727393 | gene:10728851 | methyltransferase/uroporphyrinogen-III synthase. | Glutamate-1-semialdehyde 2,1-aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.763 |
BH1495 | gsaB | gene:10727393 | gene:10726817 | methyltransferase/uroporphyrinogen-III synthase. | Glutamate-1-semialdehyde aminotransferase; BH0943. | 0.818 |
BH1495 | hemA | gene:10727393 | gene:10728958 | methyltransferase/uroporphyrinogen-III synthase. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.924 |
BH1495 | hemB | gene:10727393 | gene:10728954 | methyltransferase/uroporphyrinogen-III synthase. | Delta-aminolevulinic acid dehydratase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity). | 0.993 |
BH1495 | hemC | gene:10727393 | gene:10728956 | methyltransferase/uroporphyrinogen-III synthase. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.999 |
BH1495 | hemD | gene:10727393 | gene:10728955 | methyltransferase/uroporphyrinogen-III synthase. | Uroporphyrinogen III cosynthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.979 |
BH1495 | hemE | gene:10727393 | gene:10727096 | methyltransferase/uroporphyrinogen-III synthase. | Uroporphyrinogen III decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.953 |
BH1495 | hemL | gene:10727393 | gene:10728953 | methyltransferase/uroporphyrinogen-III synthase. | Glutamate-1-semialdehyde 2,1-aminotransferase; BH3043. | 0.834 |
BH1495 | hemX | gene:10727393 | gene:10728957 | methyltransferase/uroporphyrinogen-III synthase. | Negative effector of the concentration of HemA; BH3047. | 0.805 |
BH2941 | BH1495 | gene:10728851 | gene:10727393 | Glutamate-1-semialdehyde 2,1-aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | methyltransferase/uroporphyrinogen-III synthase. | 0.763 |
BH2941 | gsaB | gene:10728851 | gene:10726817 | Glutamate-1-semialdehyde 2,1-aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Glutamate-1-semialdehyde aminotransferase; BH0943. | 0.915 |
BH2941 | hemA | gene:10728851 | gene:10728958 | Glutamate-1-semialdehyde 2,1-aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.985 |
BH2941 | hemB | gene:10728851 | gene:10728954 | Glutamate-1-semialdehyde 2,1-aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Delta-aminolevulinic acid dehydratase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity). | 0.989 |
BH2941 | hemC | gene:10728851 | gene:10728956 | Glutamate-1-semialdehyde 2,1-aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.886 |
BH2941 | hemD | gene:10728851 | gene:10728955 | Glutamate-1-semialdehyde 2,1-aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Uroporphyrinogen III cosynthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.713 |
BH2941 | hemE | gene:10728851 | gene:10727096 | Glutamate-1-semialdehyde 2,1-aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Uroporphyrinogen III decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.440 |
BH2941 | hemL | gene:10728851 | gene:10728953 | Glutamate-1-semialdehyde 2,1-aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Glutamate-1-semialdehyde 2,1-aminotransferase; BH3043. | 0.915 |
BH3615 | hemA | gene:10729528 | gene:10728958 | Flagellar protein. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.642 |
gsaB | BH1495 | gene:10726817 | gene:10727393 | Glutamate-1-semialdehyde aminotransferase; BH0943. | methyltransferase/uroporphyrinogen-III synthase. | 0.818 |
gsaB | BH2941 | gene:10726817 | gene:10728851 | Glutamate-1-semialdehyde aminotransferase; BH0943. | Glutamate-1-semialdehyde 2,1-aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.915 |