STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ccatRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. (413 aa)    
Predicted Functional Partners:
BPSL0264
Conserved hypothetical protein; Similar to Pseudomonas pseudoalcaligenes glutathione S-transferase BphX0 SWALL:Q52037 (EMBL:D85853) (203 aa) fasta scores: E(): 7.5e-05, 30.8% id in 198 aa, and to Ralstonia solanacearum hypothetical protein rsc0086 or rs02260 SWALL:Q8Y394 (EMBL:AL646057) (229 aa) fasta scores: E(): 7.5e-42, 57% id in 207 aa.
   
   0.814
mgsA
Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
  
  
 0.745
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
 
 
 0.725
BPSL3119
Similar to Ralstonia solanacearum putative stringent starvation protein B SspB or Rsc2925 or Rs00327 SWALL:Q8XVA6 (EMBL:AL646072) (165 aa) fasta scores: E(): 2.2e-26, 55.42% id in 175 aa, and to Escherichia coli stringent starvation protein B SspB or b3228 or z4586 or ecs4101 SWALL:SSPB_ECOLI (SWALL:P25663) (165 aa) fasta scores: E(): 1.9e-13, 38.5% id in 174 aa.
  
     0.725
ftsB
Putative membrane protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
 
     0.699
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
  
    0.685
rpmF
50S ribosomal protein L32; Similar to Escherichia coli, Escherichia coli O157:H7, Salmonella typhimurium, and Salmonella typhi 50S ribosomal protein L32 RpmF SWALL:RL32_ECOLI (SWALL:P02435) (56 aa) fasta scores: E(): 2.7e-11, 62.96% id in 54 aa, and to Ralstonia solanacearum 50S ribosomal protein L32 rsc1048 or rs04194 SWALL:RL32_RALSO (SWALL:Q8Y0J6) (58 aa) fasta scores: E(): 9.8e-22, 87.93% id in 58 aa; Belongs to the bacterial ribosomal protein bL32 family.
  
    0.661
pnp
Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
 
 
 0.635
BPSL0263
Conserved hypothetical protein; Similar to the C-terminal region of Bos taurus NADH-ubiquinone oxidoreductase 39 kDa subunit, mitochondrial precursor NDUFA9 SWALL:NUEM_BOVIN (SWALL:P34943) (380 aa) fasta scores: E(): 7.2e-17, 31.14% id in 305 aa, and to the full length Ralstonia solanacearum putative NADH-ubiquinone oxidoreductase oxidoreductase protein rsc0087 or rs02261 SWALL:Q8Y393 (EMBL:AL646057) (334 aa) fasta scores: E(): 3.6e-40, 47.18% id in 337 aa.
       0.632
apaH
Bis(5'-nucleosyl)-tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.
 
  
 0.629
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.