STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glpKPutative glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (500 aa)    
Predicted Functional Partners:
glpD
Similar to Pseudomonas aeruginosa glycerol-3-phosphate dehydrogenase GlpD or pa3584 SWALL:GLPD_PSEAE (SWALL:P52111) (512 aa) fasta scores: E(): 9.6e-105, 57.91% id in 480 aa, and to Xanthomonas axonopodis glycerol-3-phosphate dehydrogenase GlpD or xac0360 SWALL:AAM35252 (EMBL:AE011662) (501 aa) fasta scores: E(): 5.5e-117, 63.25% id in 479 aa, and to Xanthomonas campestris glycerol-3-phosphate dehydrogenase GlpD or xcc0360 SWALL:AAM39679 (EMBL:AE012132) (508 aa) fasta scores: E(): 5.5e-116, 61.38% id in 505 aa; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
 0.999
glpF
Putative glycerol uptake facilitator protein; Similar to Thermus aquaticus glycerol facilitator glpF SWALL:Q93RA7 (EMBL:AB053202) (272 aa) fasta scores: E(): 7e-43, 50.64% id in 231 aa, and to Thermotoga maritima probable glycerol uptake facilitator protein GlpF or tm1429 SWALL:GLPF_THEMA (SWALL:Q9X1E3) (234 aa) fasta scores: E(): 1.1e-50, 56.83% id in 234 aa, and to Thermoanaerobacter tengcongensis glycerol uptake facilitator and related permeases GlpF or tte2003 SWALL:Q8R5R1 (EMBL:AE013151) (242 aa) fasta scores: E(): 2.3e-45, 52.11% id in 236 aa; Belongs to the MIP/aquaporin (TC 1.A [...]
 
 
 0.988
plsY
Putative membrane protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
    
 0.924
adhC
NADP-dependent alcohol dehydrogenase; Similar to Mycobacterium tuberculosis, and Mycobacterium bovis NADP-dependent alcohol dehydrogenase AdhC or Adh SWALL:ADH_MYCTU (SWALL:P31975) (346 aa) fasta scores: E(): 3.3e-68, 56% id in 350 aa, and to Xylella fastidiosa NADP-alcohol dehydrogenase XF1136 SWALL:Q9PE92 (EMBL:AE003949) (352 aa) fasta scores: E(): 3.9e-72, 58.48% id in 342 aa.
    
 0.913
BPSL2712
Putative hydrolase; Similar to Ralstonia solanacearum putative glycerophosphoryl diester phosphodiesterase, periplasmic precursor protein GlpQ or rsc0502 or rs05020 SWALL:Q8Y234 (EMBL:AL646059) (378 aa) fasta scores: E(): 4.4e-95, 68.66% id in 383 aa, and to Xanthomonas campestris glycerophosphoryl diester phosphodiesterase GlpQ or xcc4234 SWALL:AAM43450 (EMBL:AE012551) (370 aa) fasta scores: E(): 1.5e-65, 55.75% id in 339 aa.
 
  
 0.906
BPSL0498
Similar to Pseudomonas aeruginosa probable phosphotransferase protein pa3760 SWALL:Q9HXN5 (EMBL:AE004794) (842 aa) fasta scores: E(): 8e-102, 49.53% id in 860 aa. C-terminus is similar to the C-terminal region of Rhodobacter capsulatus multiphosphoryl transfer protein frub(hi) SWALL:PTF1_RHOCA (SWALL:P23388) (827 aa) fasta scores: E(): 2.7e-78, 40.73% id in 739 aa; Belongs to the PEP-utilizing enzyme family.
   
 
 0.897
BPSL1440
Putative exported protein; Similar to Ralstonia solanacearum probable ankyrin repeat harboring signal peptide protein rsc1788 or rs04187 SWALL:Q8XYH0 (EMBL:AL646066) (291 aa) fasta scores: E(): 9.2e-29, 45.74% id in 223 aa, and to the N-terminal region of Oryza sativa putative ankyrin osjnba0040e01.26 SWALL:Q9AUW0 (EMBL:AC079887) (252 aa) fasta scores: E(): 3.7e-09, 33% id in 203 aa. Note: Most of the database matches in this CDS are to the N-terminal region of ankyrin-related eukaryotic proteins.
   
 0.864
aqpZ
Aquaporin Z; Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
 
 0.858
BPSL0808
Subfamily S1C unassigned peptidase; Similar to Pseudomonas aeruginosa serine protease MucD or pa0766 SWALL:Q57155 (EMBL:U49151) (474 aa) fasta scores: E(): 1.8e-70, 47.43% id in 468 aa, and to Ralstonia solanacearum probable protease signal peptide protein rsp1552 or rs02108 SWALL:Q8XPT5 (EMBL:AL646085) (490 aa) fasta scores: E(): 2.4e-89, 58.99% id in 478 aa; Belongs to the peptidase S1C family.
   
 0.716
BPSL2006
Subfamily S1C non-peptidase homologue; Similar to Ralstonia solanacearum probable protease signal peptide protein rsp1552 or rs02108 SWALL:Q8XPT5 (EMBL:AL646085) (490 aa) fasta scores: E(): 2.9e-37, 45.17% id in 518 aa, and to Pseudomonas aeruginosa serine protease MucD or pa0766 SWALL:Q57155 (EMBL:U49151) (474 aa) fasta scores: E(): 4.1e-25, 38.26% id in 473 aa.
   
 0.716
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.