STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BPSL0706Similar to Escherichia coli aerotaxis receptor aer or air or b3072 SWALL:AER_ECOLI (SWALL:P50466) (506 aa) fasta scores: E(): 1.1e-73, 47.48% id in 516 aa, and to Ralstonia solanacearum probable aerotaxis sensor receptor aer or rsp1224 or rs03168 SWALL:Q8XQK0 (EMBL:AL646083) (514 aa) fasta scores: E(): 1.3e-103, 61.5% id in 517 aa, and to Yersinia pestis putative methyl-accepting chemotaxis protein ypo1644 SWALL:Q8ZFP9 (EMBL:AJ414149) (526 aa) fasta scores: E(): 1e-86, 53.17% id in 519 aa. (583 aa)    
Predicted Functional Partners:
cheA
Chemotaxis two-component sensor kinase CheA; Similar to Escherichia coli chemotaxis protein CheA or b1888 SWALL:CHEA_ECOLI (SWALL:P07363) (654 aa) fasta scores: E(): 9.5e-76, 56.14% id in 741 aa.
 
 0.990
cheW2
Chemotaxis protein CheW2; Similar to Escherichia coli, and Escherichia coli O157:H7 chemotaxis protein CheW or b1887 or z2941 or ecs2597 SWALL:CHEW_ECOLI (SWALL:P07365) (167 aa) fasta scores: E(): 4.1e-30, 59.86% id in 147 aa, and to Burkholderia pseudomallei chemotaxis protein CheW SWALL:O05183 (EMBL:U92493) (175 aa) fasta scores: E(): 9.4e-32, 57.31% id in 164 aa. Note: Also similar to BPSL3305 cheW (176 aa) fasta scores: E(): 9.3e-31, 60.131% identity in 153 aa overlap.
 
 0.986
cheW
Chemotaxis protein CheW; Previously characterised as Burkholderia pseudomallei chemotaxis protein CheW SWALL:O05183 (EMBL:U92493) (175 aa) fasta scores: E(): 2.1e-66, 100% id in 175 aa, and to Escherichia coli chemotaxis protein CheW or b1887 or z2941 or ecs2597 SWALL:CHEW_ECOLI (SWALL:P07365) (167 aa) fasta scores: E(): 9.8e-39, 71.81% id in 149 aa.
 
 0.986
cheR
Chemotaxis protein methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.
 
 0.984
cheB
Chemotaxis protein-glutamate methylesterase protein CheB; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 0.982
cheD
Putative chemotaxis protein; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.
 
  0.977
aer
Aerotaxis receptor; Similar to Escherichia coli aerotaxis receptor Aer or Air or b3072 SWALL:AER_ECOLI (SWALL:P50466) (506 aa) fasta scores: E(): 7.6e-83, 51.65% id in 515 aa, and to Ralstonia solanacearum probable aerotaxis sensor receptor rsp1224 or rs03168 SWALL:Q8XQK0 (EMBL:AL646083) (514 aa) fasta scores: E(): 8.2e-120, 69.84% id in 514 aa.
 
 
0.908
cheY1
Chemotaxis two-component response regulator CheY1; Similar to Rhizobium meliloti chemotaxis regulator CheY or R00638 or Smc03006 SWALL:Q52879 (EMBL:U13166) (121 aa) fasta scores: E(): 7.1e-15, 43.8% id in 121 aa.
  
  0.880
BPSS1871
Putative chemotaxis-related histidine kinase protein; Similar to Thermotoga maritima chemotaxis protein CheA or tm0702 SWALL:CHEA_THEMA (SWALL:Q56310) (671 aa) fasta scores: E(): 2.2e-33, 27.4% id in 708 aa, and to Rhizobium loti chemotaxis histidine kinase mll9511 SWALL:Q98PD0 (EMBL:AP003017) (757 aa) fasta scores: E(): 1.1e-104, 49.07% id in 864 aa.
 
 
 0.876
cheB2
Putative chemotaxis-related methylesterase protein; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 
 0.794
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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