STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BPSL0734Putative two-component transcriptional response regulator; From codon 189-321 similar to Xanthomonas axonopodis two-component system regulatory protein colR or xac1221 SWALL:AAM36093 (EMBL:AE011752) (238 aa) fasta scores: E(): 0.0042, 24.21% id in 128 aa, and to Ralstonia solanacearum probable two-component system response regulator transcription regulator protein rsc1073 or rs04004 SWALL:Q8Y0H1 (EMBL:AL646062) (237 aa) fasta scores: E(): 0.0087, 30.46% id in 128 aa. (320 aa)    
Predicted Functional Partners:
BPSL0732
Putative two-component regulator histidine sensor kinase; Similar to Rhodobacter sphaeroides DMSO/TMAO-sensor kinase dorS SWALL:O30740 (EMBL:AF016236) (815 aa) fasta scores: E(): 4.6e-25, 33.24% id in 385 aa, and to Caulobacter crescentus sensor histidine kinase / response regulator cc0723 SWALL:Q9AA83 (EMBL:AE005747) (591 aa) fasta scores: E(): 1.6e-27, 30.34% id in 412 aa, and to Xanthomonas campestris two-component system sensor protein xcc2360 SWALL:AAM41638 (EMBL:AE012344) (1364 aa) fasta scores: E(): 3.7e-26, 29.7% id in 404 aa.
 
   0.943
BPSL0733
Putative exported protein; C-terminus is similar to the C-terminal region of Agrobacterium tumefaciens hypothetical protein atu3496 or agr_l_2662 SWALL:Q8UA78 (EMBL:AE009279) (168 aa) fasta scores: E(): 4.3e-11, 34.78% id in 138 aa. Weakly similar to to Pseudomonas aeruginosa hypothetical protein pa2869 SWALL:Q9HZX7 (EMBL:AE004713) (162 aa) fasta scores: E(): 2.8e-07, 28.48% id in 158 aa, and to Vibrio cholerae hypothetical protein vc1933 SWALL:Q9KQR5 (EMBL:AE004269) (156 aa) fasta scores: E(): 7e-06, 27.04% id in 159 aa, and to Vibrio cholerae hypothetical protein Vca0075 vca0075 SWAL [...]
 
     0.917
BPSL2025
Putative two component regulatory system, sensor kinase; Similar to the C-terminal region of Escherichia coli sensor protein RcsC or b2218 SWALL:RCSC_ECOLI (SWALL:P14376) (949 aa) fasta scores: E(): 2e-37, 32.94% id in 513 aa, and of Salmonella typhi sensor protein RcsC or sty2496 SWALL:RCSC_SALTI (SWALL:Q56128) (948 aa) fasta scores: E(): 1.2e-35, 32.82% id in 521 aa.
  
 
 0.833
BPSS1940
Similar to Caulobacter crescentus sensory box histidine kinase/response regulator cc3225 SWALL:Q9A3H9 (EMBL:AE005986) (731 aa) fasta scores: E(): 9.5e-57, 35.17% id in 688 aa, and to Pseudomonas putida sensor histidine kinase/response regulator pp3651 SWALL:AAN69251 (EMBL:AE016787) (727 aa) fasta scores: E(): 6.1e-51, 33.19% id in 729 aa.
  
 
 0.833
BPSS2246
Putative sensor kinase/response regulator fusion protein; Similar to Anabaena sp. two-component hybrid sensor and regulator alr3442 SWALL:Q8YRK4 (EMBL:AP003593) (865 aa) fasta scores: E(): 1.3e-49, 30.58% id in 680 aa, and to Ralstonia solanacearum probable composite two-component regulatory rsp1676 or rs02235 SWALL:Q8XPG5 (EMBL:AL646086) (796 aa) fasta scores: E(): 1e-42, 32.65% id in 640 aa.
  
 
 0.833
BPSS2345
Sensory kinase protein; No significant database matches to the full length CDS. C-terminus is similar to the C-terminal regions of Brucella melitensis sensory transduction protein kinase bmei0947 SWALL:Q8YH57 (EMBL:AE009535) (767 aa) fasta scores: E(): 1.7e-39, 35.64% id in 418 aa, and Caulobacter crescentus sensory box histidine kinase/response regulator cc2874 SWALL:Q9A4G0 (EMBL:AE005952) (794 aa) fasta scores: E(): 1.6e-34, 33.82% id in 541 aa. Possible alternative translational start site.
 
 
 0.764
BPSS1356
Hypothetical protein; No significant database matches.
  
     0.752
BPSL1128
Putative lipoprotein; No significant database matches.
  
    0.722
BPSS0135
Similar to Ralstonia solanacearum hypothetical protein rsp1479 or rs03064 SWALL:Q8XQ07 (EMBL:AL646085) (150 aa) fasta scores: E(): 2e-17, 45.86% id in 133 aa.
  
     0.709
BPSL1859
Putative membrane protein; No significant database matches.
  
     0.706
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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