STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BPSL0750Hypothetical protein; C-terminal region is similar to Escherichia coli O157:H7 hypothetical protein z0331 or ecs0295 SWALL:Q8X7J2 (EMBL:AE005203) (188 aa) fasta scores: E(): 4.3e-09, 27.52% id in 178 aa. (602 aa)    
Predicted Functional Partners:
BPSL1970
Calcineurin-like phosphoesterase; Similar to Pseudomonas aeruginosa hypothetical protein pa0544 SWALL:Q9I5Z2 (EMBL:AE004490) (247 aa) fasta scores: E(): 1.9e-09, 36.27% id in 317 aa. Note: the central region of BPSL1970 does not present any similarities in the databases.
  
 0.997
BPSL0748
Hypothetical protein; No significant database matches to the full length CDS. N-terminal region is similar to Escherichia coli O157:H7 hypothetical protein z0325 or ecs0290 SWALL:Q8X7K6 (EMBL:AE005203) (138 aa) fasta scores: E(): 7.4e-11, 37.98% id in 129 aa, and the C-terminal region is similar to Escherichia coli O157:H7 hypothetical protein z0326 or ecs0291 SWALL:Q8X7K5 (EMBL:AE005203) (205 aa) fasta scores: E(): 7e-12, 31.25% id in 192 aa. CDS is a possible fusion protein.
 
     0.954
BPSL0749
Hypothetical protein; Similar to Escherichia coli O157:H7 hypothetical protein z0327 or ecs0292 SWALL:Q8X7K4 (EMBL:AE005203) (152 aa) fasta scores: E(): 6.8e-05, 22.44% id in 147 aa.
 
     0.954
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.950
recQ
Similar to Escherichia coli ATP-dependent DNA helicase RecQ or b3822 SWALL:RECQ_ECOLI (SWALL:P15043) (607 aa) fasta scores: E(): 2.8e-77, 44.62% id in 614 aa, and to Ralstonia solanacearum probable ATP-dependent DNA helicase protein RecQ or Rsc3025 or Rs04732 SWALL:Q8XV07 (EMBL:AL646073) (637 aa) fasta scores: E(): 7.7e-178, 72.38% id in 630 aa.
  
 0.936
BPSL0118
Similar to Escherichia coli DNA topoisomerase III TopB SWALL:TOP3_ECOLI (SWALL:P14294) (653 aa) fasta scores: E(): 2.1e-57, 33.71% id in 620 aa, and to Ralstonia solanacearum probable DNA topoisomerase III protein rsc0066 or rs02245 SWALL:Q8Y3B4 (EMBL:AL646057) (877 aa) fasta scores: E(): 0, 80.04% id in 872 aa.
  
 0.856
recA
Putative recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.854
BPSS2211
Similar to Pseudomonas aeruginosa probable ATP-dependent DNA ligase pa2138 SWALL:Q9I1X7 (EMBL:AE004641) (840 aa) fasta scores: E(): 3.9e-54, 42.03% id in 1123 aa, and to Xanthomonas campestris ATP-dependent DNA ligase xcc0105 SWALL:Q8PE76 (EMBL:AE012104) (1001 aa) fasta scores: E(): 4.3e-34, 35.13% id in 1147 aa. Note: There are some fragments in this CDS that present no similarities to any of the database matches.
   
 0.831
BPSL0763
Putative helicase SNF2 family protein; Similar to Bacteroides nodosus putative DEAH ATP-dependent helicase SWALL:O32494 (EMBL:U20246) (965 aa) fasta scores: E(): 2.4e-28, 28.84% id in 780 aa, and to Xanthomonas campestris helicase xcc0524 SWALL:AAM39840 (EMBL:AE012150) (967 aa) fasta scores: E(): 1.8e-11, 25.36% id in 962 aa, and to Halobacterium sp. similar to Escherichia coli vng5141g or vng6139G SWALL:O52003 (EMBL:AF016485) (979 aa) fasta scores: E(): 1.9e-10, 27.33% id in 995 aa. Possible alternative translational start site.
 
 
 0.782
BPSL1437
Similar to Escherichia coli DNA polymerase III, delta' subunit HolB or b1099 SWALL:HOLB_ECOLI (SWALL:P28631) (334 aa) fasta scores: E(): 4e-11, 34.82% id in 290 aa, and to Ralstonia solanacearum probable DNA polymerase III rsc1785 or rs04183 SWALL:Q8XYH3 (EMBL:AL646066) (336 aa) fasta scores: E(): 8.5e-47, 55.71% id in 341 aa.
  
 0.710
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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