STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kynUConserved hypothetical protein; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (416 aa)    
Predicted Functional Partners:
kynA
Putative tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
 
 
 0.997
kynB
Conserved hypothetical protein; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation.
 
 
 0.996
BPSL0071
Putative catalase; Has an organic peroxide-dependent peroxidase activity. Belongs to the catalase family.
   
 
 0.902
katB
Pfam match to entry PF00072 response_reg, Response regulator receiver domain, score 85.7, E-value 6.3e-23; Belongs to the catalase family.
   
 
 0.902
katE
Catalase HPII; Serves to protect cells from the toxic effects of hydrogen peroxide.
   
 
 0.902
katG
Catalase-peroxidase protein; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity. Displays also NADH oxidase, isoniazid hydrazine lyase and isonicotinoyl-NAD synthase activity.
     
  0.900
BPSS2156
Similar to Streptomyces coelicolor hypothetical protein sco6307 sco6307 or scif3.09C SWALL:Q93RT4 (EMBL:AL939127) (320 aa) fasta scores: E(): 2.6e-12, 36.18% id in 351 aa.
  
  
 0.804
BPSS2041
Similar to Streptomyces coelicolor hypothetical protein SCO4016 or 2SC10A7.20 SWALL:Q9ADP0 (EMBL:AL939118) (317 aa) fasta scores: E(): 0.00057, 28.57% id in 329 aa.
  
  
 0.543
suhB
Inositol-1-monophosphatase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 inositol-1-monophosphatase SuhB or SsyA SWALL:SUHB_ECOLI (SWALL:P22783) (267 aa) fasta scores: E(): 1.7e-47, 51.96% id in 254 aa, and to Ralstonia solanacearum probable inositol monophosphatase rsc1160 or rs04755 SWALL:Q8Y084 (EMBL:AL646063) (270 aa) fasta scores: E(): 2.7e-70, 68.16% id in 267 aa.
      
 0.505
hmgA
Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
  
  
 0.501
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
Server load: low (26%) [HD]