STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
talBTransaldolase B; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (317 aa)    
Predicted Functional Partners:
tktA
Transketolase 1; Similar to Escherichia coli transketolase 1 TktA or Tkt or b2935 SWALL:TKT1_ECOLI (SWALL:P27302) (663 aa) fasta scores: E(): 4.8e-167, 63.48% id in 671 aa, and to Ralstonia solanacearum probable transketolase protein rsc2750 or rs00104 SWALL:Q8XVS9 (EMBL:AL646071) (675 aa) fasta scores: E(): 4.5e-192, 72.99% id in 674 aa; Belongs to the transketolase family.
 
 0.995
pgi
Glucose-6-phosphate isomerase; Similar to Escherichia coli, and Escherichia coli O157:H7 glucose-6-phosphate isomerase Pgi or b4025 or z5623 or ecs5008 SWALL:G6PI_ECOLI (SWALL:P11537) (549 aa) fasta scores: E(): 2.5e-100, 49.9% id in 543 aa, and to Deinococcus radiodurans glucose-6-phosphate isomerase dr1742 SWALL:G6PI_DEIRA (SWALL:Q9RTL8) (541 aa) fasta scores: E(): 7.5e-120, 57.22% id in 540 aa.
  
 
 0.974
cbbA
Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
  
 
 0.961
BPSS1957
Similar to Escherichia coli 6-phosphofructokinase isozyme 2 PfkB or b1723 SWALL:K6P2_ECOLI (SWALL:P06999) (309 aa) fasta scores: E(): 1.8e-31, 39.48% id in 309 aa, and to Salmonella typhimurium 6-phosphofructokinase II Pfkb or stm1326 SWALL:Q8ZPT5 (EMBL:AE008757) (310 aa) fasta scores: E(): 7e-32, 39.15% id in 309 aa; Belongs to the carbohydrate kinase PfkB family.
   
 
 0.947
fbp
Similar to Alcaligenes eutrophus fructose-1,6-bisphosphatase, chromosomal CbbfC or cfxF SWALL:F16P_ALCEU (SWALL:P19911) (364 aa) fasta scores: E(): 1.2e-79, 60.41% id in 341 aa, and to Pseudomonas aeruginosa fructose-1,6-bisphosphatase Fbp or pa5110 SWALL:Q9HU73 (EMBL:AE004923) (336 aa) fasta scores: E(): 4.9e-96, 72.23% id in 335 aa.
  
 
 0.943
BPSL2222
Putative transketolase; Similar to Thermoplasma acidophilum probable transketolase ta0617 SWALL:Q9HKI2 (EMBL:AL445064) (316 aa) fasta scores: E(): 2.6e-24, 32.67% id in 303 aa, and to Pyrococcus abyssi transketolase C-terminal section Tkt2 or pab0296 SWALL:Q9V1I1 (EMBL:AJ248284) (317 aa) fasta scores: E(): 9.6e-22, 32.65% id in 294 aa.
  
 
 0.934
BPSL2223
Putative transketolase; Similar to Fusobacterium nucleatum transketolase subunit A fn0294 SWALL:Q8RGJ9 (EMBL:AE010542) (270 aa) fasta scores: E(): 2.2e-33, 42.53% id in 268 aa, and to Methanococcus jannaschii putative transketolase N-terminal section mj0681 SWALL:TKTN_METJA (SWALL:Q58094) (274 aa) fasta scores: E(): 2.5e-29, 38.62% id in 277 aa.
    
 0.933
gnd
6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
 
 
 0.931
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 0.928
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate.
    
 0.927
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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