STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
cbiDPutative cobalamin biosynthesis-related protein; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (363 aa)    
Predicted Functional Partners:
cobJ
Similar to Pseudomonas denitrificans precorrin-3b C17-methyltransferase CobJ SWALL:COBJ_PSEDE (SWALL:P21640) (254 aa) fasta scores: E(): 1.1e-35, 52.2% id in 249 aa, and to C-terminal region to Mycobacterium tuberculosis cobalamin biosynthesis protein rv2066 or mt2126 or mtcy49.05 SWALL:COBI_MYCTU (SWALL:Q10677) (508 aa) fasta scores: E(): 1.8e-31, 40% id in 365 aa.
 
 
 0.999
cobK
Similar to Rhodococcus erythropolis precorrin-6X reductase CobK SWALL:COBK_RHOER (SWALL:Q53139) (248 aa) fasta scores: E(): 1.2e-30, 45.56% id in 248 aa, and to Streptomyces coelicolor putative precorrin-6X reductase sco3283 or sce39.33C SWALL:Q9X8F6 (EMBL:AL049573) (255 aa) fasta scores: E(): 5.9e-32, 48.81% id in 252 aa.
 
 0.998
cobL
Similar to Pseudomonas denitrificans precorrin-6Y C5,15-methyltransferase [decarboxylating] cobL SWALL:COBL_PSEDE (SWALL:P21921) (413 aa) fasta scores: E(): 7.9e-67, 49.62% id in 401 aa, and to Brucella melitensis precorrin-6Y C5,15-methyltransferase bmei0716 SWALL:Q8YHT0 (EMBL:AE009513) (401 aa) fasta scores: E(): 1.9e-90, 61.71% id in 397 aa.
 
  
 0.997
BPSL1771
Putative cobalamin biosynthesis related protein; Similar to C-terminal region of Ralstonia solanacearum putative precorrin methylase protein CbiG or rsp0619 or rs03748 SWALL:Q8XS62 (EMBL:AL646079) (254 aa) fasta scores: E(): 4.8e-06, 46.85% id in 143 aa, and to Pseudomonas denitrificans CobE protein SWALL:COBE_PSEDE (SWALL:P21635) (154 aa) fasta scores: E(): 0.36, 31.97% id in 147 aa. Possible gene remnant.
 
 
 0.985
cobQ
Putative cobyric acid synthase protein; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.968
cobM
Similar to Rhodococcus erythropolis precorrin-4 C11-methyltransferase CobM SWALL:COBM_RHOER (SWALL:Q53138) (249 aa) fasta scores: E(): 3.3e-43, 52.69% id in 241 aa, and to Pseudomonas denitrificans precorrin-4 C11-methyltransferase CobM SWALL:COBM_PSEDE (SWALL:P21922) (253 aa) fasta scores: E(): 1.1e-41, 52.43% id in 246 aa.
 
  
 0.965
cobH
Similar to Pseudomonas denitrificans precorrin-8X methylmutase CobH SWALL:COBH_PSEDE (SWALL:P21638) (210 aa) fasta scores: E(): 3.7e-44, 66.33% id in 202 aa, and to Brucella melitensis precorrin-8X methylmutase bmei0714 SWALL:Q8YHT2 (EMBL:AE009513) (208 aa) fasta scores: E(): 3.5e-55, 75.48% id in 208 aa.
 
  
 0.958
cobI
Precorrin-2 C20-methyltransferase; Methylates precorrin-2 at the C-20 position to produce precorrin-3A.
 
  
 0.938
cobB
Similar to Pseudomonas aeruginosa cobyrinic acid A,C-diamide synthase CobB or pa1273 SWALL:COBB_PSEAE (SWALL:Q9I471) (435 aa) fasta scores: E(): 2.8e-48, 49.81% id in 528 aa, and to Bacillus megaterium cobyrinic acid A,C-diamide synthase CobB or CbiA SWALL:COBB_BACME (SWALL:O87698) (460 aa) fasta scores: E(): 4.4e-16, 29.29% id in 536 aa. Note: This CDS contains an unique region from approximately residue 225 to approximately residue 340 that has no similarity to any of the database matches.
 
  
 0.893
cobD
Putative cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
  
 0.823
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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