STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
amrRTetR family regulatory protein; Almost identical to Burkholderia pseudomallei regulator AmrR SWALL:O87934 (EMBL:AF072887) (187 aa) fasta scores: E(): 1e-64, 99.42% id in 173 aa. Similar to Ralstonia solanacearum putative AcrAB operon repressor transcription regulator protein AcrR or rsc0012 or rs01834 SWALL:Q8Y3G8 (EMBL:AL646057) (219 aa) fasta scores: E(): 4.2e-21, 38.22% id in 225 aa. Note: This CDS is longer than the previously sequenced AmrR in its C-terminal region, it is possible that the previous sequence submitted to the databases had a sequencing error that led to a frameshift [...] (223 aa)    
Predicted Functional Partners:
amrA
Almost identical to Burkholderia pseudomallei putative membrane fusion protein AmrA SWALL:O87935 (EMBL:AF072887) (399 aa) fasta scores: E(): 7.7e-133, 99.74% id in 399 aa. Similar to Escherichia coli, and Escherichia coli O157:H7 acriflavine resistance protein A precursor AcrA or MtcA or Lir or b0463 or z0578 or ecs0516 SWALL:ACRA_ECO57 (SWALL:P31223) (397 aa) fasta scores: E(): 3.5e-43, 40.1% id in 384 aa; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
   
 0.816
amrB
Multidrug efflux system transporter protein AmrB; Almost identical to previously sequenced Burkholderia pseudomallei putative transporter AmrB SWALL:O87936 (EMBL:AF072887) (1043 aa) fasta scores: E(): 0, 99.8% id in 1043 aa. Similar to Escherichia coli acriflavine resistance protein B AcrB or AcrE or b0462 SWALL:ACRB_ECOLI (SWALL:P31224) (1049 aa) fasta scores: E(): 5.5e-199, 51.79% id in 1033 aa.
     
 0.783
BPSL1802
Multidrug efflux system putative membrane lipoprotein; Similar to Pseudomonas aeruginosa outer membrane protein precursor OprM or OprK or pa0427 SWALL:OPRM_PSEAE (SWALL:Q51487) (485 aa) fasta scores: E(): 2.3e-59, 46.39% id in 485 aa, and to Xanthomonas axonopodis outer membrane protein OprM or xac2842 SWALL:AAM37687 (EMBL:AE011925) (503 aa) fasta scores: E(): 9.5e-65, 47.54% id in 488 aa.
     
 0.737
oprB
Similar to Pseudomonas aeruginosa outer membrane protein OprM precursor pa0427 SWALL:OPRM_PSEAE (SWALL:Q51487) (485 aa) fasta scores: E(): 4.1e-85, 55.67% id in 476 aa, and to Xanthomonas axonopodis outer membrane protein xac2842 SWALL:AAM37687 (EMBL:AE011925) (503 aa) fasta scores: E(): 5.8e-84, 53.72% id in 497 aa.
     
 0.579
BPSS1333
Conserved hypothetical protein; Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
     
 0.499
oxa
Beta-lactamase precursor; Almost identical to the previously sequenced Burkholderia pseudomallei beta-lactamase precursor Oxa SWALL:CAD32565 (EMBL:AJ488303) (269 aa) fasta scores: E(): 2.2e-111, 99.62% id in 269 aa. Similar to Pseudomonas aeruginosa beta-lactamase Oxa-18 precursor SWALL:BLOI_PSEAE (SWALL:O07293) (275 aa) fasta scores: E(): 2.4e-37, 43.07% id in 267 aa.
  
   
 0.468
BPSL3085
Similar to Ralstonia solanacearum hypothetical protein Rsc3157 or Rs00441 SWALL:Q8XUN0 (EMBL:AL646074) (278 aa) fasta scores: E(): 5e-95, 83.75% id in 277 aa.
      
 0.440
BPSS0290
Similar to Burkholderia cepacia putative transcriptional regulator CeoR SWALL:Q8VL17 (EMBL:AY008288) (334 aa) fasta scores: E(): 8.5e-123, 91.01% id in 334 aa, and to Salmonella typhi putative transcriptional regulator sty1386 SWALL:Q8Z7A3 (EMBL:AL627270) (301 aa) fasta scores: E(): 8.7e-49, 43.79% id in 290 aa; Belongs to the LysR transcriptional regulatory family.
    
 
 0.433
BPSL0731
LysR family transcriptional regulator; Similar to previously sequenced Burkholderia cepacia putative transcriptional regulator CeoR ceoR SWALL:Q8VL17 (EMBL:AY008288) (334 aa) fasta scores: E(): 1.1e-81, 64.39% id in 323 aa, and to Ralstonia solanacearum probable transcription regulator protein rsp1110 or rs02618 SWALL:Q8XQV8 (EMBL:AL646082) (315 aa) fasta scores: E(): 1.8e-59, 49.33% id in 300 aa, and to Pseudomonas aeruginosa probable transcriptional regulator pa2877 SWALL:Q9HZX0 (EMBL:AE004714) (297 aa) fasta scores: E(): 2.1e-49, 45.57% id in 294 aa; Belongs to the LysR transcriptio [...]
    
 
 0.431
ftsI-3
Putative penicillin-binding protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
      
 0.411
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.